Long term follow-up results of Chinese prescription "Shen Yang" in the combined and sequential treatment of oral squamous cell carcinoma

Guo chu Lin, Wei liu Qiu, Chang yu Lu, Yi qin Guo, Yang Cao, Walter Guralnick, Chung cheng Hsich, Thomas Albert, William C. Wood, Edward Everts

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Abstract

OBJECTIVE: To evaluate the long term therapeutic effect of Chinese prescription "Shen Yang" in the combined and sequential therapy for oral squamous cell carcinoma cases. METHODS: There are 238 cases with oral squamous cell carcinoma. They were divided into two groups randomly as "Shen Yang" experiment group and control group (placebo). 25 cases were precluded from the experiment group. 17 of them were due to unexperiment of taking "Shen Yang" within three months. 8 cases were lost of follow-up. 213 patients were included in this study. Among them, 104 cases in experiment group, and 109 cases in control one.Patients in both groups were followed-up for 5-10 years. Their life-curve was calculated by means of Logrank method. RESULTS: The survival rate of "Shen Yang" group was improved by 8.46%, 9.26%, 9.04% and 8.57% for 3-year, 5-year, 8-year and 10-year survival rates. But the differences between the two groups were not statistically significant (P=0.1936, P>0.05). CONCLUSION: Chinese prescription of "Shen Yang" had a tendency to improve the survival rate for oral squamous cell carcinoma patients.

Original languageEnglish (US)
Pages (from-to)321-323
Number of pages3
JournalShanghai kou qiang yi xue = Shanghai journal of stomatology
Volume12
Issue number5
StatePublished - Oct 2003

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lin, G. C., Qiu, W. L., Lu, C. Y., Guo, Y. Q., Cao, Y., Guralnick, W., Hsich, C. C., Albert, T., Wood, W. C., & Everts, E. (2003). Long term follow-up results of Chinese prescription "Shen Yang" in the combined and sequential treatment of oral squamous cell carcinoma. Shanghai kou qiang yi xue = Shanghai journal of stomatology, 12(5), 321-323.