Long term follow-up results of Chinese prescription "Shen Yang" in the combined and sequential treatment of oral squamous cell carcinoma

Guo chu Lin, Wei liu Qiu, Chang yu Lu, Yi qin Guo, Yang Cao, Walter Guralnick, Chung cheng Hsich, Thomas Albert, William C. Wood, Edward Everts

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

OBJECTIVE: To evaluate the long term therapeutic effect of Chinese prescription "Shen Yang" in the combined and sequential therapy for oral squamous cell carcinoma cases. METHODS: There are 238 cases with oral squamous cell carcinoma. They were divided into two groups randomly as "Shen Yang" experiment group and control group (placebo). 25 cases were precluded from the experiment group. 17 of them were due to unexperiment of taking "Shen Yang" within three months. 8 cases were lost of follow-up. 213 patients were included in this study. Among them, 104 cases in experiment group, and 109 cases in control one.Patients in both groups were followed-up for 5-10 years. Their life-curve was calculated by means of Logrank method. RESULTS: The survival rate of "Shen Yang" group was improved by 8.46%, 9.26%, 9.04% and 8.57% for 3-year, 5-year, 8-year and 10-year survival rates. But the differences between the two groups were not statistically significant (P=0.1936, P>0.05). CONCLUSION: Chinese prescription of "Shen Yang" had a tendency to improve the survival rate for oral squamous cell carcinoma patients.

Original languageEnglish (US)
Pages (from-to)321-323
Number of pages3
JournalShanghai kou qiang yi xue = Shanghai journal of stomatology
Volume12
Issue number5
StatePublished - 2003
Externally publishedYes

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Prescriptions
Squamous Cell Carcinoma
Survival Rate
Therapeutic Uses
Therapeutics
Placebos
Control Groups

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Long term follow-up results of Chinese prescription "Shen Yang" in the combined and sequential treatment of oral squamous cell carcinoma. / Lin, Guo chu; Qiu, Wei liu; Lu, Chang yu; Guo, Yi qin; Cao, Yang; Guralnick, Walter; Hsich, Chung cheng; Albert, Thomas; Wood, William C.; Everts, Edward.

In: Shanghai kou qiang yi xue = Shanghai journal of stomatology, Vol. 12, No. 5, 2003, p. 321-323.

Research output: Contribution to journalArticle

Lin, Guo chu ; Qiu, Wei liu ; Lu, Chang yu ; Guo, Yi qin ; Cao, Yang ; Guralnick, Walter ; Hsich, Chung cheng ; Albert, Thomas ; Wood, William C. ; Everts, Edward. / Long term follow-up results of Chinese prescription "Shen Yang" in the combined and sequential treatment of oral squamous cell carcinoma. In: Shanghai kou qiang yi xue = Shanghai journal of stomatology. 2003 ; Vol. 12, No. 5. pp. 321-323.
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abstract = "OBJECTIVE: To evaluate the long term therapeutic effect of Chinese prescription {"}Shen Yang{"} in the combined and sequential therapy for oral squamous cell carcinoma cases. METHODS: There are 238 cases with oral squamous cell carcinoma. They were divided into two groups randomly as {"}Shen Yang{"} experiment group and control group (placebo). 25 cases were precluded from the experiment group. 17 of them were due to unexperiment of taking {"}Shen Yang{"} within three months. 8 cases were lost of follow-up. 213 patients were included in this study. Among them, 104 cases in experiment group, and 109 cases in control one.Patients in both groups were followed-up for 5-10 years. Their life-curve was calculated by means of Logrank method. RESULTS: The survival rate of {"}Shen Yang{"} group was improved by 8.46{\%}, 9.26{\%}, 9.04{\%} and 8.57{\%} for 3-year, 5-year, 8-year and 10-year survival rates. But the differences between the two groups were not statistically significant (P=0.1936, P>0.05). CONCLUSION: Chinese prescription of {"}Shen Yang{"} had a tendency to improve the survival rate for oral squamous cell carcinoma patients.",
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T1 - Long term follow-up results of Chinese prescription "Shen Yang" in the combined and sequential treatment of oral squamous cell carcinoma

AU - Lin, Guo chu

AU - Qiu, Wei liu

AU - Lu, Chang yu

AU - Guo, Yi qin

AU - Cao, Yang

AU - Guralnick, Walter

AU - Hsich, Chung cheng

AU - Albert, Thomas

AU - Wood, William C.

AU - Everts, Edward

PY - 2003

Y1 - 2003

N2 - OBJECTIVE: To evaluate the long term therapeutic effect of Chinese prescription "Shen Yang" in the combined and sequential therapy for oral squamous cell carcinoma cases. METHODS: There are 238 cases with oral squamous cell carcinoma. They were divided into two groups randomly as "Shen Yang" experiment group and control group (placebo). 25 cases were precluded from the experiment group. 17 of them were due to unexperiment of taking "Shen Yang" within three months. 8 cases were lost of follow-up. 213 patients were included in this study. Among them, 104 cases in experiment group, and 109 cases in control one.Patients in both groups were followed-up for 5-10 years. Their life-curve was calculated by means of Logrank method. RESULTS: The survival rate of "Shen Yang" group was improved by 8.46%, 9.26%, 9.04% and 8.57% for 3-year, 5-year, 8-year and 10-year survival rates. But the differences between the two groups were not statistically significant (P=0.1936, P>0.05). CONCLUSION: Chinese prescription of "Shen Yang" had a tendency to improve the survival rate for oral squamous cell carcinoma patients.

AB - OBJECTIVE: To evaluate the long term therapeutic effect of Chinese prescription "Shen Yang" in the combined and sequential therapy for oral squamous cell carcinoma cases. METHODS: There are 238 cases with oral squamous cell carcinoma. They were divided into two groups randomly as "Shen Yang" experiment group and control group (placebo). 25 cases were precluded from the experiment group. 17 of them were due to unexperiment of taking "Shen Yang" within three months. 8 cases were lost of follow-up. 213 patients were included in this study. Among them, 104 cases in experiment group, and 109 cases in control one.Patients in both groups were followed-up for 5-10 years. Their life-curve was calculated by means of Logrank method. RESULTS: The survival rate of "Shen Yang" group was improved by 8.46%, 9.26%, 9.04% and 8.57% for 3-year, 5-year, 8-year and 10-year survival rates. But the differences between the two groups were not statistically significant (P=0.1936, P>0.05). CONCLUSION: Chinese prescription of "Shen Yang" had a tendency to improve the survival rate for oral squamous cell carcinoma patients.

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