TY - CHAP
T1 - Long-Term Depression (LTD)
T2 - Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms
AU - Lüscher, C.
AU - Frerking, M.
PY - 2009
Y1 - 2009
N2 - Long-term depression (LTD) of excitatory synaptic transmission represents a mechanism by which synapses can undergo an activity-dependent weakening of their strength. There are at least two broad classes of LTD, distinguished by the glutamate receptor that is required for LTD induction, which may be either of the NMDA (NMDAR) or metabotropic (mGluR) type. For this article we therefore distinguish NMDAR-LTD from mGluR-LTD and present contrasting properties for their induction, expression, and maintenance.
AB - Long-term depression (LTD) of excitatory synaptic transmission represents a mechanism by which synapses can undergo an activity-dependent weakening of their strength. There are at least two broad classes of LTD, distinguished by the glutamate receptor that is required for LTD induction, which may be either of the NMDA (NMDAR) or metabotropic (mGluR) type. For this article we therefore distinguish NMDAR-LTD from mGluR-LTD and present contrasting properties for their induction, expression, and maintenance.
UR - http://www.scopus.com/inward/record.url?scp=84882891119&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84882891119&partnerID=8YFLogxK
U2 - 10.1016/B978-008045046-9.01205-5
DO - 10.1016/B978-008045046-9.01205-5
M3 - Chapter
AN - SCOPUS:84882891119
SN - 9780080450469
SP - 527
EP - 532
BT - Encyclopedia of Neuroscience
PB - Elsevier Ltd
ER -