Long term consequences of low birthweight on postnatal growth, adiposity and brain weight at maturity in sheep

Samantha Louey, Megan L. Cock, Richard Harding

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Low birth weight (LBW) as a result of restricted fetal growth increases the risk for later metabolic diseases and adiposity. However the relationship between LBW and postnatal growth and adult body composition has not been fully investigated. We have used sheep to determine the effects of LBW on postnatal growth and body composition at maturity. LBW was induced by twinning and placental embolization. At birth, LBW lambs were 38% lighter than controls (2.8 ± 0.2 vs 4.4 ± 0.3 kg, P

Original languageEnglish (US)
Pages (from-to)59-68
Number of pages10
JournalJournal of Reproduction and Development
Volume51
Issue number1
DOIs
StatePublished - Feb 2005
Externally publishedYes

Fingerprint

low birth weight
Adiposity
Low Birth Weight Infant
adiposity
Sheep
brain
Weights and Measures
sheep
Brain
Growth
Body Composition
body composition
Metabolic Diseases
fetal development
metabolic diseases
Fetal Development
lambs
Parturition

Keywords

  • Adiposity
  • Birth weight
  • Body composition
  • Fetal growth restriction
  • Leptin

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Reproductive Medicine

Cite this

Long term consequences of low birthweight on postnatal growth, adiposity and brain weight at maturity in sheep. / Louey, Samantha; Cock, Megan L.; Harding, Richard.

In: Journal of Reproduction and Development, Vol. 51, No. 1, 02.2005, p. 59-68.

Research output: Contribution to journalArticle

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