Long-lived plasma cells: A mechanism for maintaining persistent antibody production

Mark K. Slifka, Rafi Ahmed

    Research output: Contribution to journalArticlepeer-review

    232 Scopus citations

    Abstract

    Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

    Original languageEnglish (US)
    Pages (from-to)252-258
    Number of pages7
    JournalCurrent opinion in immunology
    Volume10
    Issue number3
    DOIs
    StatePublished - Jun 1998

    ASJC Scopus subject areas

    • Immunology and Allergy
    • Immunology

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