Long-lived plasma cells: A mechanism for maintaining persistent antibody production

Mark K. Slifka, Rafi Ahmed

Research output: Contribution to journalArticlepeer-review

240 Scopus citations

Abstract

Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

Original languageEnglish (US)
Pages (from-to)252-258
Number of pages7
JournalCurrent opinion in immunology
Volume10
Issue number3
DOIs
StatePublished - Jun 1998
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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