Long-circulating iron oxides for MR imaging

Ralph Weissleder, Alexei Bogdanov, Edward A. Neuwelt, Mikhail Papisov

Research output: Contribution to journalReview article

352 Scopus citations


A variety of iron oxide preparations with long blood half-lives have been synthesized for MR imaging. Potential applications of these agents include MR angiography, RES imaging, target specific imaging and neuronal transport imaging. This chapter reviews types of iron oxide and mechanisms that are responsible for a prolonged plasma half-life.

Original languageEnglish (US)
Pages (from-to)321-334
Number of pages14
JournalAdvanced Drug Delivery Reviews
Issue number2-3
StatePublished - Sep 1995


  • Iron oxide
  • MR imaging

ASJC Scopus subject areas

  • Pharmaceutical Science

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