@article{267aaa793df34c34bd044b23e14e3a3e,
title = "Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q",
abstract = "Metabotropic glutamate receptors (GRMs) are neurotransmitter receptors that respond to glutamate stimulations by activating GTP-binding proteins and modulating second-messenger cascades. Eight related GRMs have been identified to date. In this study, we have mapped GRM3 and GRM8 to human chromosome 7q21.1-q21.2 and 7q31.3-q32.1, respectively, using somatic cell hybrid and fluorescence in situ hybridization analysis. A yeast artificial chromosome contig was constructed surrounding the genes, allowing their location to he integrated into the genetic and physical map of chromosome 7.",
author = "Scherer, {Stephen W.} and Duvoisin, {Robert M.} and Rainer Kuhn and Heng, {Henry H.Q.} and Elena Belloni and Tsui, {Lap Chee}",
note = "Funding Information: The work is supported by funds from the Canadian Genome Analysis and Technology (CGAT) Program (to L.-C.T). R.M.D is supported by NIH Grant EY09534 and by a Career Development Award from Research to Prevent Blindness, Inc. Special thanks to Sylvia Soder and Jack Huizenga of the CGAT YAC Core Facility for technical assistance, to Dr. J.-P. Pin for generously providing the rat mGluR3 probe, and to Jean Weissenbach for unpublished information on some of the genetic markers.",
year = "1996",
month = jan,
day = "15",
doi = "10.1006/geno.1996.0036",
language = "English (US)",
volume = "31",
pages = "230--233",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "2",
}