Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31

Torbjoern G. Nygaard; Deborah Raymond; Caiping Chen; Ichizo Nishino; Paul E. Greene; Danna Jennings; Gary A. Heiman; Christine Klein; Rachel J. Saunders-Pullman; Patricia Kramer; Laurie J. Ozelius; Susan B. Bressman

doi:10.1002/1531-8249(199911)46:5<794::AID-ANA19>3.0.CO;2-2

Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31

Torbjoern G. Nygaard, Deborah Raymond, Caiping Chen, Ichizo Nishino, Paul E. Greene, Danna Jennings, Gary A. Heiman, Christine Klein, Rachel J. Saunders-Pullman, Patricia Kramer, Laurie J. Ozelius, Susan B. Bressman

Neurology

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Abstract

Essential myoclonus-dystonia is a neurological condition characterized by myoclonic and dystonic muscle contractions and the absence of other neurological signs or laboratory abnormalities; it is often responsive to alcohol. The disorder may be familial with apparent autosomal dominant inheritance. We report a large kindred with essential familial myoclonus- dystonia and map a locus for the disorder to a 28-cM region of chromosome 7q21-q31.

Original language	English (US)
Pages (from-to)	794-798
Number of pages	5
Journal	Annals of Neurology
Volume	46
Issue number	5
DOIs	https://doi.org/10.1002/1531-8249(199911)46:5<794::AID-ANA19>3.0.CO;2-2
State	Published - 1999

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1002/1531-8249(199911)46:5<794::AID-ANA19>3.0.CO;2-2

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title = "Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31",

abstract = "Essential myoclonus-dystonia is a neurological condition characterized by myoclonic and dystonic muscle contractions and the absence of other neurological signs or laboratory abnormalities; it is often responsive to alcohol. The disorder may be familial with apparent autosomal dominant inheritance. We report a large kindred with essential familial myoclonus- dystonia and map a locus for the disorder to a 28-cM region of chromosome 7q21-q31.",

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T1 - Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31

AU - Nygaard, Torbjoern G.

AU - Raymond, Deborah

AU - Chen, Caiping

AU - Nishino, Ichizo

AU - Greene, Paul E.

AU - Jennings, Danna

AU - Heiman, Gary A.

AU - Klein, Christine

AU - Saunders-Pullman, Rachel J.

AU - Kramer, Patricia

AU - Ozelius, Laurie J.

AU - Bressman, Susan B.

PY - 1999

Y1 - 1999

N2 - Essential myoclonus-dystonia is a neurological condition characterized by myoclonic and dystonic muscle contractions and the absence of other neurological signs or laboratory abnormalities; it is often responsive to alcohol. The disorder may be familial with apparent autosomal dominant inheritance. We report a large kindred with essential familial myoclonus- dystonia and map a locus for the disorder to a 28-cM region of chromosome 7q21-q31.

AB - Essential myoclonus-dystonia is a neurological condition characterized by myoclonic and dystonic muscle contractions and the absence of other neurological signs or laboratory abnormalities; it is often responsive to alcohol. The disorder may be familial with apparent autosomal dominant inheritance. We report a large kindred with essential familial myoclonus- dystonia and map a locus for the disorder to a 28-cM region of chromosome 7q21-q31.

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Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31

Abstract

ASJC Scopus subject areas

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