Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31

Torbjoern G. Nygaard, Deborah Raymond, Caiping Chen, Ichizo Nishino, Paul E. Greene, Danna Jennings, Gary A. Heiman, Christine Klein, Rachel J. Saunders-Pullman, Patricia Kramer, Laurie J. Ozelius, Susan B. Bressman

Research output: Contribution to journalArticle

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Abstract

Essential myoclonus-dystonia is a neurological condition characterized by myoclonic and dystonic muscle contractions and the absence of other neurological signs or laboratory abnormalities; it is often responsive to alcohol. The disorder may be familial with apparent autosomal dominant inheritance. We report a large kindred with essential familial myoclonus- dystonia and map a locus for the disorder to a 28-cM region of chromosome 7q21-q31.

Original languageEnglish (US)
Pages (from-to)794-798
Number of pages5
JournalAnnals of Neurology
Volume46
Issue number5
DOIs
StatePublished - 1999

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Chromosomes
Dystonic Disorders
Muscle Contraction
Genes
Alcohols
Myoclonic dystonia

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Nygaard, T. G., Raymond, D., Chen, C., Nishino, I., Greene, P. E., Jennings, D., ... Bressman, S. B. (1999). Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31. Annals of Neurology, 46(5), 794-798. https://doi.org/10.1002/1531-8249(199911)46:5<794::AID-ANA19>3.0.CO;2-2

Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31. / Nygaard, Torbjoern G.; Raymond, Deborah; Chen, Caiping; Nishino, Ichizo; Greene, Paul E.; Jennings, Danna; Heiman, Gary A.; Klein, Christine; Saunders-Pullman, Rachel J.; Kramer, Patricia; Ozelius, Laurie J.; Bressman, Susan B.

In: Annals of Neurology, Vol. 46, No. 5, 1999, p. 794-798.

Research output: Contribution to journalArticle

Nygaard, TG, Raymond, D, Chen, C, Nishino, I, Greene, PE, Jennings, D, Heiman, GA, Klein, C, Saunders-Pullman, RJ, Kramer, P, Ozelius, LJ & Bressman, SB 1999, 'Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31', Annals of Neurology, vol. 46, no. 5, pp. 794-798. https://doi.org/10.1002/1531-8249(199911)46:5<794::AID-ANA19>3.0.CO;2-2
Nygaard, Torbjoern G. ; Raymond, Deborah ; Chen, Caiping ; Nishino, Ichizo ; Greene, Paul E. ; Jennings, Danna ; Heiman, Gary A. ; Klein, Christine ; Saunders-Pullman, Rachel J. ; Kramer, Patricia ; Ozelius, Laurie J. ; Bressman, Susan B. / Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31. In: Annals of Neurology. 1999 ; Vol. 46, No. 5. pp. 794-798.
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