Liposomal amphotericin B-induced hypotension leading to ST segment elevated myocardial infarction

Harsh Golwala; Nishit Patel; Soni Zacharias; Pedro Lozano

doi:10.1097/MJT.0b013e3182192e70

Liposomal amphotericin B-induced hypotension leading to ST segment elevated myocardial infarction

Harsh Golwala, Nishit Patel, Soni Zacharias, Pedro Lozano

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We hereby report a short case of 71-year-old gentleman who developed ST segment elevation myocardial infarction shortly after starting the infusion of liposomal amphotericin B for disseminated histoplasmosis. We also discuss the novel pathogenesis of specific liposomal component of amphotericin B that contributed to the acute cardiopulmonary compromise in our patient leading to subsequent myocardial infarction.

Original language	English (US)
Pages (from-to)	e157-e158
Journal	American Journal of Therapeutics
Volume	18
Issue number	5
DOIs	https://doi.org/10.1097/MJT.0b013e3182192e70
State	Published - Sep 1 2011
Externally published	Yes

Keywords

hypotension
liposomal amphotericin B
myocardial infarction
pseudoallergy

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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10.1097/MJT.0b013e3182192e70

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abstract = "We hereby report a short case of 71-year-old gentleman who developed ST segment elevation myocardial infarction shortly after starting the infusion of liposomal amphotericin B for disseminated histoplasmosis. We also discuss the novel pathogenesis of specific liposomal component of amphotericin B that contributed to the acute cardiopulmonary compromise in our patient leading to subsequent myocardial infarction.",

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AU - Lozano, Pedro

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AB - We hereby report a short case of 71-year-old gentleman who developed ST segment elevation myocardial infarction shortly after starting the infusion of liposomal amphotericin B for disseminated histoplasmosis. We also discuss the novel pathogenesis of specific liposomal component of amphotericin B that contributed to the acute cardiopulmonary compromise in our patient leading to subsequent myocardial infarction.

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KW - liposomal amphotericin B

KW - myocardial infarction

KW - pseudoallergy

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Liposomal amphotericin B-induced hypotension leading to ST segment elevated myocardial infarction

Abstract

Keywords

ASJC Scopus subject areas

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