Lipopolysaccharide-induced middle ear inflammation disrupts the cochlear intra-strial fluid-blood barrier through down-regulation of tight junction proteins

Medicine & Life Sciences

• Tight Junction Proteins 100%
• Otitis Media 86%
• Cochlea 81%
• Lipopolysaccharides 66%
• Down-Regulation 54%
• Otitis 33%
• Middle Ear 28%
• Inner Ear 28%
• FITC-albumin 15%
• Bacteriolysis 14%
• High-Frequency Hearing Loss 12%
• Endothelial Cells 12%
• Homeostasis 12%
• Stria Vascularis 12%
• Animal Models 12%
• Macrophages 12%
• cadherin 5 11%
• Occludin 11%
• Pericytes 10%
• Water-Electrolyte Balance 10%
• Inflammation 10%
• Blood Vessels 10%
• Herpes Zoster 9%
• Melanocytes 9%
• Tight Junctions 9%
• Cellular Structures 9%
• Permeability 7%
• Cell Culture Techniques 6%
• Immunohistochemistry 6%
• Cytokines 5%
• Animals 4%
• Infections 4%
• In Vitro Techniques 3%

Agriculture & Biology

• middle ear 99%
• tight junctions 97%
• lipopolysaccharides 74%
• inflammation 70%
• fluids 58%
• blood 45%
• inner ear 32%
• proteins 26%
• blood vessels 21%
• endothelial cells 17%
• macrophages 15%
• homeostasis 14%
• infection 13%
• cadherins 11%
• melanocytes 10%
• hearing 9%
• immunohistochemistry 8%
• cytokines 8%
• albumins 7%
• animal models 7%
• permeability 7%
• animals 7%
• cell culture 6%
• cells 5%
• mice 4%
• assays 4%

Chemical Compounds

• Lipopolysaccharide 85%
• Protein 32%
• Monolayer 29%
• Permeability 10%