Light stimulation of iris tyrosinase r487w7 =eyes in vivo

T. P. Dryja, G. P. Kimball, Daniel Albert

Research output: Contribution to journalArticle

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Although exposure of epidermal melanocytes to ultraviolet radiation is known to increase tyrosinase activity, a similar effect has never been demonstrated for the iris. This paper presents evidence that light stimulates tyrosinase activity in iris melanocytes in rabbits. Levels of iris tyrosinase were found to be greater in eyes of rabbits exposed to light for 6 weeks than in eye of rabbits maintained in darkness. Despite increasing tyrosinase levels, exposure to light produced no clinically observable change in iris color.

Original languageEnglish (US)
Pages (from-to)559-562
Number of pages4
JournalInvestigative Ophthalmology and Visual Science
Issue number5
Publication statusPublished - Dec 1 1980
Externally publishedYes


ASJC Scopus subject areas

  • Ophthalmology

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