Leukocytes in mammary development and cancer

Lisa M. Coussens, Jeffrey W. Pollard

Research output: Contribution to journalArticlepeer-review

112 Scopus citations

Abstract

Leukocytes, of both the innate and adaptive lineages, are normal cellular components of all tissues. These important cells not only are critical for regulating normal tissue homeostasis, but also are significant paracrine regulators of all physiologic and pathologic tissue repair processes. This article summarizes recent insights regarding the trophic roles of leukocytes at each stage of mammary gland development and during cancer development, with a focus on Murids and humans.

Original languageEnglish (US)
Pages (from-to)1-22
Number of pages22
JournalCold Spring Harbor Perspectives in Biology
Volume3
Issue number3
DOIs
StatePublished - Mar 2011
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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