Lesions of the female reproductive tract in Japanese macaque (Macaca fuscata) from two captive colonies

Andrew J. Gall, June E. Olds, Arno Wünschmann, Laura E. Selmic, James Rasmussen, Anne Lewis

    Research output: Contribution to journalArticle

    Abstract

    Reproductive lesions have been described in various nonhuman primate species, including rhesus macaques (Macaca mulatta), cynomolgus macaques (Macaca fascicularis), baboons (Papio spp.), squirrel monkeys (Saimiri sciureus), and chimpanzees (Pan spp.); however, there are few publications describing reproductive disease and pathology in Japanese macaques (Macaca fuscata). A retrospective evaluation of postmortem reports for two captive M. fuscata populations housed within zoos from 1982 through 2015 was completed, comparing reproductive diseases diagnosed by gross pathology and histopathology. Disease prevalence, organs affected, and median age at death between the two institutions was also compared. Fifteen female captive M. fuscata, ranging in age from 15 to 29 yr were identified with reproductive tract lesions, including endometriosis, endometritis, leiomyoma, leiomyosarcoma, and adenomyosis. No significant differences were identified in disease prevalence, organs affected, and median age of death between the two institutions. Endometriosis was the most common disease process identified and was found in 10 of the 15 cases (66.7%), followed by leiomyoma (4 of 15; 26.7%). In four cases (26.7%), severe endometriosis and secondary hemorrhage was indicated as the cause of death or the primary reason for humane euthanasia. These findings were compared with a separate population of Japanese macaques managed within a research facility in the United States, with a prevalence of endometriosis of 7.6%. This study discusses possible risk factors and potential treatment options for the management of endometriosis in captive M. fuscata.

    Original languageEnglish (US)
    Pages (from-to)79-85
    Number of pages7
    JournalJournal of Zoo and Wildlife Medicine
    Volume49
    Issue number1
    DOIs
    StatePublished - Mar 1 2018

    Fingerprint

    Macaca fuscata
    Macaca
    Endometriosis
    lesions (animal)
    Saimiri
    Papio
    Leiomyoma
    reproductive disorders
    Macaca mulatta
    Macaca fascicularis
    disease prevalence
    death
    Pathology
    Adenomyosis
    Endometritis
    leiomyosarcoma
    Euthanasia
    Pan troglodytes
    Leiomyosarcoma
    Pan (Pongidae)

    Keywords

    • Endometriosis
    • Japanese macaque
    • Leiomyoma
    • Macaca fuscata
    • Reproduction

    ASJC Scopus subject areas

    • Animal Science and Zoology
    • veterinary(all)

    Cite this

    Lesions of the female reproductive tract in Japanese macaque (Macaca fuscata) from two captive colonies. / Gall, Andrew J.; Olds, June E.; Wünschmann, Arno; Selmic, Laura E.; Rasmussen, James; Lewis, Anne.

    In: Journal of Zoo and Wildlife Medicine, Vol. 49, No. 1, 01.03.2018, p. 79-85.

    Research output: Contribution to journalArticle

    Gall, Andrew J. ; Olds, June E. ; Wünschmann, Arno ; Selmic, Laura E. ; Rasmussen, James ; Lewis, Anne. / Lesions of the female reproductive tract in Japanese macaque (Macaca fuscata) from two captive colonies. In: Journal of Zoo and Wildlife Medicine. 2018 ; Vol. 49, No. 1. pp. 79-85.
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