Abstract
Leptin is thought to relay metabolic information to the hypothalamic-pituitary-gonadal axis and to participate in the neuroendocrine control of puberty. To help elucidate the underlying mechanism, Cheung et al. recently performed a diverse series of experiments, the results of which undermine the prevailing hypothesis that leptin acts as a metabolic trigger for the initiation of puberty. Instead, their results suggest that leptin is one of many permissive metabolic factors that allow pubertal development to proceed.
Original language | English (US) |
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Pages (from-to) | 428-429 |
Number of pages | 2 |
Journal | Trends in Endocrinology and Metabolism |
Volume | 12 |
Issue number | 10 |
DOIs | |
State | Published - 2001 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology