Legionella dismantles linear ubiquitin

Rune Busk Damgaard, Jonathan Pruneda

Research output: Contribution to journalArticle

Abstract

Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that Legionella pneumophila — the causative agent of Legionnaires’ disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses.

Original languageEnglish (US)
Pages (from-to)1244-1245
Number of pages2
JournalNature Microbiology
Volume4
Issue number8
DOIs
StatePublished - Aug 1 2019

Fingerprint

Legionella
Ubiquitin
Legionnaires' Disease
Legionella pneumophila
Bacterial Infections
Enzymes

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Applied Microbiology and Biotechnology
  • Genetics
  • Microbiology (medical)
  • Cell Biology

Cite this

Legionella dismantles linear ubiquitin. / Damgaard, Rune Busk; Pruneda, Jonathan.

In: Nature Microbiology, Vol. 4, No. 8, 01.08.2019, p. 1244-1245.

Research output: Contribution to journalArticle

Damgaard, Rune Busk ; Pruneda, Jonathan. / Legionella dismantles linear ubiquitin. In: Nature Microbiology. 2019 ; Vol. 4, No. 8. pp. 1244-1245.
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