Legionella dismantles linear ubiquitin

Rune Busk Damgaard; Jonathan N. Pruneda

doi:10.1038/s41564-019-0515-5

Legionella dismantles linear ubiquitin

Rune Busk Damgaard, Jonathan N. Pruneda

Molecular Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that Legionella pneumophila — the causative agent of Legionnaires’ disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses.

Original language	English (US)
Pages (from-to)	1244-1245
Number of pages	2
Journal	Nature Microbiology
Volume	4
Issue number	8
DOIs	https://doi.org/10.1038/s41564-019-0515-5
State	Published - Aug 1 2019

ASJC Scopus subject areas

Microbiology
Immunology
Applied Microbiology and Biotechnology
Genetics
Microbiology (medical)
Cell Biology

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10.1038/s41564-019-0515-5

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title = "Legionella dismantles linear ubiquitin",

abstract = "Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that Legionella pneumophila — the causative agent of Legionnaires{\textquoteright} disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses.",

author = "Damgaard, {Rune Busk} and Pruneda, {Jonathan N.}",

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Legionella dismantles linear ubiquitin

Abstract

ASJC Scopus subject areas

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