Legionella dismantles linear ubiquitin

Rune Busk Damgaard, Jonathan Pruneda

Research output: Contribution to journalArticle

Abstract

Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that Legionella pneumophila — the causative agent of Legionnaires’ disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses.

Original languageEnglish (US)
Pages (from-to)1244-1245
Number of pages2
JournalNature Microbiology
Volume4
Issue number8
DOIs
Publication statusPublished - Aug 1 2019

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ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Applied Microbiology and Biotechnology
  • Genetics
  • Microbiology (medical)
  • Cell Biology

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