Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that Legionella pneumophila — the causative agent of Legionnaires’ disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses.
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology
- Microbiology (medical)
- Cell Biology