Lead optimization of nerve-specific fluorophores for image-guided nerve sparing surgical procedures

Connor W. Barth, Lei G. Wang, Antonio Montano, Alexander L. Antaris, Alwin Klaassen, Jonathan Sorger, Darcy A. Kerr, Eric R. Henderson, Adam W.G. Alani, Summer L. Gibbs

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nerve damage is a major complication of surgery, causing pain and loss of function. We have identified novel near-infrared nerve-specific fluorophores that provide excellent nerve contrast with the ability to identify buried nerve tissue.

Original languageEnglish (US)
Title of host publicationOptical Molecular Probes, Imaging and Drug Delivery, OMP 2021
PublisherThe Optical Society
ISBN (Electronic)9781557528209
StatePublished - 2021
EventOptical Molecular Probes, Imaging and Drug Delivery, OMP 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, United States
Duration: Apr 12 2021Apr 16 2021

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceOptical Molecular Probes, Imaging and Drug Delivery, OMP 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021
Country/TerritoryUnited States
CityVirtual, Online
Period4/12/214/16/21

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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