Lead exposure and early child neurodevelopment among children 12–24 months in Kinshasa, the Democratic Republic of Congo

Espérance Kashala-Abotnes, Pépé Penghele Mumbere, Jeannette Mukanya Mishika, Ally Omba Ndjukendi, Davin Beya Mpaka, Makila Mabe Guy Bumoko, Tharcisse Kalula Kayembe, Désiré Tshala-Katumbay, Théodore Kayembe Kazadi, Daniel Luwa E.Andjafono Okitundu

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Childhood lead exposure remains a problem in developing countries, and little is known about its effects on early child neurodevelopment and temperament in the Democratic Republic of Congo (DRC). We, therefore, conducted this study to determine the association between lead exposure and the neurodevelopment and behaviour of children aged 12–24 months in Kinshasa, DRC. A cross-sectional study was conducted between February and June 2012, and parents of 104 children were invited to participate. Blood lead levels (BLLs) of each child were tested using the flame atomic spectrophotometry method. All children were subject to a clinical examination and assessed with two selected early child neurodevelopmental tools, the Gensini–Gavito and the baby characteristics questionnaire, to measure their neurodevelopment and temperament. Detectable BLLs ranged from 1 to 30 μg/dl with a geometric mean of 6.9 (SD 4.8) μg/dl. BLLs at 5–9 and ≥10 μg/dl were significantly associated with the child temperament (p <0.05). Perinatal and maternal factors did not seem to affect early child neurodevelopment and temperament. Children exposed to lead were reported with more temperament difficulties at even blood lead levels <10 μg/dl, suggesting the need for preventive and intervention measures to reduce lead exposure among children in Kinshasa, DRC.

Original languageEnglish (US)
Pages (from-to)1361-1367
Number of pages7
JournalEuropean Child and Adolescent Psychiatry
Volume25
Issue number12
DOIs
StatePublished - Dec 1 2016

Keywords

  • Childhood
  • Kinshasa/DRC
  • Lead exposure
  • Neurodevelopment
  • Temperament

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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    Kashala-Abotnes, E., Mumbere, P. P., Mishika, J. M., Ndjukendi, A. O., Mpaka, D. B., Bumoko, M. M. G., Kayembe, T. K., Tshala-Katumbay, D., Kazadi, T. K., & Okitundu, D. L. E. A. (2016). Lead exposure and early child neurodevelopment among children 12–24 months in Kinshasa, the Democratic Republic of Congo. European Child and Adolescent Psychiatry, 25(12), 1361-1367. https://doi.org/10.1007/s00787-016-0860-3