Latex allergy in non-spina bifida patients: Unfamiliar intra-operative anaphylaxis

Greggory H. Burrow, Kent A. Vincent, Joseph (Ivan) Krajbich, Michael D. Aiona

Research output: Contribution to journalArticle

Abstract

Background: The medical literature has described the prevalence of latex allergy in the spina bifida population and its implications for surgical intervention. We report three cases of severe and unexpected intra-operative anaphylaxis secondary to latex exposure in non-spina bifida patients. Methods: A retrospective review of case notes identified three non-spina bifida patients who suffered intra-operative anaphylaxis due to latex allergy. Personal and telephone interview and patient chart review was performed to detail a past history of multiple latex exposure, atopy, the anaphylaxis event and the postoperative outcome. Results: Three non-spina bifida patients are described. One suffered a cardiopulmonary arrest, the remaining two patients had severe vascular hypotension and airway resistance that was only relieved after administration of vasoconstrictors and bronchodilators. Postoperatively, all three tested strongly positive to latex allergen testing. Each patient had a history of multiple surgical latex exposure and specific allergies or allergic-type symptoms pre-operatively. Conclusion: We believe that the predictors of a severe allergic reaction to latex with surgical exposure in non-spina bifida patients may be similar to those predictors known in the spina bifida population. Identification of such at-risk patients will reduce the risk of significant intra-operative morbidity and possible mortality by the introduction of a latex-free operating environment.

Original languageEnglish (US)
Pages (from-to)183-185
Number of pages3
JournalJournal of Applied Microbiology
Volume87
Issue number2
StatePublished - 1999
Externally publishedYes

Fingerprint

Latex Hypersensitivity
anaphylaxis
Anaphylaxis
latex
hypersensitivity
Latex
spina bifida
Spinal Dysraphism
Hypersensitivity
bronchodilators
atopy
vasoconstrictor agents
cardiac arrest
Airway Resistance
hypotension
Bronchodilator Agents
Vasoconstrictor Agents
allergens
Heart Arrest
blood vessels

Keywords

  • Anaphylaxis
  • Intra-operative
  • Latex
  • Non-spina bifida

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Applied Microbiology and Biotechnology
  • Biotechnology
  • Microbiology

Cite this

Latex allergy in non-spina bifida patients : Unfamiliar intra-operative anaphylaxis. / Burrow, Greggory H.; Vincent, Kent A.; Krajbich, Joseph (Ivan); Aiona, Michael D.

In: Journal of Applied Microbiology, Vol. 87, No. 2, 1999, p. 183-185.

Research output: Contribution to journalArticle

Burrow, Greggory H. ; Vincent, Kent A. ; Krajbich, Joseph (Ivan) ; Aiona, Michael D. / Latex allergy in non-spina bifida patients : Unfamiliar intra-operative anaphylaxis. In: Journal of Applied Microbiology. 1999 ; Vol. 87, No. 2. pp. 183-185.
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