Latent growth models matched to research questions to answer questions about dynamics of change in multiple processes

Graciela Muniz-Terrera, Annie Robitaille, Amanda Kelly, Boo Johansson, Scott Hofer, Andrea Piccinin

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Objectives Given theoretical and methodological advances that propose hypothesis about change in one or multiple processes, analytical methods for longitudinal data have been developed that provide researchers with various options for analyzing change over time. In this paper, we revisited several latent growth curve models that may be considered to answer questions about repeated measures of continuous variables, which may be operationalized as time-varying covariates or outcomes. Study Design and Setting To illustrate each of the models discussed and how to interpret parameter estimates, we present examples of each method discussed using cognitive and blood pressure measures from a longitudinal study of aging, the Origins of Variance in the Old-Old study. Results and Conclusion Although statistical models are helpful tools to test theoretical hypotheses about the dynamics between multiple processes, the choice of model and its specification will influence results and conclusions made.

Original languageEnglish (US)
Pages (from-to)158-166
Number of pages9
JournalJournal of Clinical Epidemiology
Volume82
DOIs
StatePublished - Feb 1 2017

Keywords

  • Bivariate latent growth model
  • Latent growth model
  • Longitudinal models
  • Repeated measures, Multilevel models
  • Time-varying covariates

ASJC Scopus subject areas

  • Epidemiology

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