Late occurrence of drop metastasis to the spine in a case of esthesioneuroblastoma: Case report

Abigail J. Rao, S. Humayun Gultekin, Edward A. Neuwelt, Hector R. Cintrón-Colón, Brian T. Ragel

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Esthesioneuroblastoma is an aggressive neuroectodermal tumor that originates from the olfactory mucosa and often recurs locally. Distant metastasis of esthesioneuroblastoma has been described, but there are few reports of drop metastasis to the spinal cord. Here, we report a case of multiple drop metastases to the cervical, thoracic, and lumbar regions of the spinal cord that occurred 18 years after resection and radiotherapy of the original anterior cranial fossa lesion. There was no evidence of local recurrence. The symptomatic lesion was treated with resection and adjuvant chemotherapy. The options available for treatment of this disease are summarized with a review of the few reported cases of spinal metastasis of esthesioneuroblastoma.

Original languageEnglish (US)
Pages (from-to)571-575
Number of pages5
JournalJournal of Neurosurgery: Spine
Volume15
Issue number5
DOIs
StatePublished - Nov 1 2011

Keywords

  • Drop metastasis
  • Esthesioneuroblastoma
  • Olfactory neuroblastoma
  • Oncology
  • Recurrence
  • Spine

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology

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