Late complications of aortic valve replacement with cloth covered, composite seat prostheses. A six year appraisal

Albert Starr, L. I. Bonchek, R. P. Anderson, J. A. Wood, R. D. Chapman

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Advanced actuarial techniques are used to analyze early and late results in a closely followed series of 396 patients who received a cloth covered, composite seat aortic prosthesis. Late mortality and various complications are carefully assessed, and most late deaths are unrelated to the prosthesis. 116 patients with Model 2310-2320 prostheses who received warfarin postoperatively had no thromboembolic complications in 360 patient years of followup (average, 3.1 yr per patient); 134 patients who had the same prosthesis but did not receive warfarin had 9 emboli per 100 patient years (average followup, 1.7 yr per patient; total 228 patient years). By comparison in 9 years' experience with non cloth covered Model 1200-1260 valves, 132 patients had 4.0 emboli per 100 patient years (average followup, 5.1 yr; total, 673 patient years). The safety of cloth covered valves is clearly enhanced by concomitant use of anticoagulants; the possibility that antiplatelet drugs may suffice has not yet been demonstrated. Strut cloth wear was found at reoperation in 10 patients. The Model 2400 composite strut ('track') valve with a narrow metal track on the inner surface of each strut prevents this complication.

Original languageEnglish (US)
Pages (from-to)289-300
Number of pages12
JournalAnnals of Thoracic Surgery
Volume19
Issue number3
DOIs
StatePublished - 1975

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Aortic Valve
Prostheses and Implants
Warfarin
Embolism
Platelet Aggregation Inhibitors
Reoperation
Anticoagulants
Metals
Safety

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Late complications of aortic valve replacement with cloth covered, composite seat prostheses. A six year appraisal. / Starr, Albert; Bonchek, L. I.; Anderson, R. P.; Wood, J. A.; Chapman, R. D.

In: Annals of Thoracic Surgery, Vol. 19, No. 3, 1975, p. 289-300.

Research output: Contribution to journalArticle

Starr, Albert ; Bonchek, L. I. ; Anderson, R. P. ; Wood, J. A. ; Chapman, R. D. / Late complications of aortic valve replacement with cloth covered, composite seat prostheses. A six year appraisal. In: Annals of Thoracic Surgery. 1975 ; Vol. 19, No. 3. pp. 289-300.
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