Late Complications of Aortic Valve Replacement with Cloth-Covered, Composite-Seat Prostheses: A Six-Year Appraisal

Albert Starr, Lawrence I. Bonchek, Richard P. Anderson, James A. Wood, Richard D. Chapman

Research output: Contribution to journalArticle

30 Scopus citations


Advanced actuarial techniques are used to analyze early and late results in a closely followed series of 396 patients who received a cloth-covered, composite-seat aortic prosthesis. Late mortality and various complications are carefully assessed, and most late deaths are seen to be unrelated to the prosthesis. One hundred sixteen patients with Model 2310–2320 prostheses who received warfarin postoperatively had no thromboembolic complications in 360 patient-years of follow-up (average, 3.1 years per patient); 134 patients who had the same prosthesis but did not receive warfarin had 9 emboli per 100 patient-years (average follow-up, 1.7 years per patient; total, 228 patient-years). By comparison, in 9 years' experience with non-cloth-covered Model 1200–1260 valves, 132 patients had 4.0 emboli per 100 patient-years (average follow-up, 5.1 years; total, 673 patient-years). The safety of cloth-covered valves is clearly enhanced by concomitant use of anticoagulants; the possibility that antiplatelet drugs may suffice has not yet been demonstrated. Strut cloth wear was found at reoperation in 10 patients. The Model 2400 composite strut (“track”) valve with a narrow metal track on the inner surface of each strut prevents this complication.

Original languageEnglish (US)
Pages (from-to)289-300
Number of pages12
JournalAnnals of Thoracic Surgery
Issue number3
StatePublished - Jan 1 1975


ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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