‘Lady Windermere's counterpart? Pulmonary nontuberculous mycobacteria in men with bronchiectasis

Jennifer H. Ku, Gregory Ranches, Sarah A.R. Siegel, Kevin L. Winthrop

Research output: Contribution to journalArticle

Abstract

Pulmonary nontuberculous mycobacterial (NTM) disease occurs frequently in older women, and phenotypes of men with NTM disease are largely undescribed. We conducted a case–control study of 34 men with non-cystic fibrosis pulmonary NTM disease (cases), and three male and female control groups with or without NTM disease. Cases were median 71 years of age (range 30–94) and mostly non-Hispanic white (85.3%). These men had similarly low BMI as their female NTM patient counterparts, which was lower than both healthy men (p < 0.001) and bronchiectatic men without NTM (p = 0.06). Kyphoscoliosis was also more common in cases than healthy men (p= 0.007) or bronchiectatic men without NTM (p = 0.02). Our study was the first study to our knowledge to examine demographic features and phenotypes of men with NTM disease. Larger studies are needed to ascertain whether these phenotypes are characteristic of men with NTM disease.

Original languageEnglish (US)
Article number114916
JournalDiagnostic Microbiology and Infectious Disease
DOIs
StateAccepted/In press - Jan 1 2019

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Nontuberculous Mycobacteria
Bronchiectasis
Lung
Phenotype
Pulmonary Fibrosis
Demography
Control Groups

Keywords

  • Atypical mycobacteria
  • Bronchiectasis
  • Kyphoscoliosis
  • Nontuberculous mycobacteria
  • Pectus excavatum
  • Pulmonary infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

‘Lady Windermere's counterpart? Pulmonary nontuberculous mycobacteria in men with bronchiectasis. / Ku, Jennifer H.; Ranches, Gregory; Siegel, Sarah A.R.; Winthrop, Kevin L.

In: Diagnostic Microbiology and Infectious Disease, 01.01.2019.

Research output: Contribution to journalArticle

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