Lack of Effect of Selenium on Glycolytic and Citric Acid Cycle Intermediates in Rat Kidney and Liver

T. R. Shearer

doi:10.3181/00379727-144-37663

Lack of Effect of Selenium on Glycolytic and Citric Acid Cycle Intermediates in Rat Kidney and Liver

T. R. Shearer

Integrative Biosciences

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The concentrations of glycolytic and citric acid cycle intermediates were measured in the livers and kidneys from a selenium group of rats receiving 4 ppm Se in their drinking water. Compared to the concentrations of intermediates in the livers and kidneys from a control group of rats yoke-fed to the selenium rats, no metabolic changes were observed. It was concluded that growth depression and changes in eating and drinking behavior caused by selenium were not due to enzyme inhibition within glycolysis or the citric acid cycle. The author wishes to thank Mrs. Muriel Pallay and Mrs. Nadya Smejtek for technical assistance.

Original language	English (US)
Pages (from-to)	688-691
Number of pages	4
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	144
Issue number	2
DOIs	https://doi.org/10.3181/00379727-144-37663
State	Published - Nov 1973

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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title = "Lack of Effect of Selenium on Glycolytic and Citric Acid Cycle Intermediates in Rat Kidney and Liver",

abstract = "The concentrations of glycolytic and citric acid cycle intermediates were measured in the livers and kidneys from a selenium group of rats receiving 4 ppm Se in their drinking water. Compared to the concentrations of intermediates in the livers and kidneys from a control group of rats yoke-fed to the selenium rats, no metabolic changes were observed. It was concluded that growth depression and changes in eating and drinking behavior caused by selenium were not due to enzyme inhibition within glycolysis or the citric acid cycle. The author wishes to thank Mrs. Muriel Pallay and Mrs. Nadya Smejtek for technical assistance.",

author = "Shearer, {T. R.}",

note = "Funding Information: Supported by U.S. Public Health Service Grant DE-03536. 11 1973 144 2 688 691 ",

year = "1973",

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AU - Shearer, T. R.

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PY - 1973/11

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N2 - The concentrations of glycolytic and citric acid cycle intermediates were measured in the livers and kidneys from a selenium group of rats receiving 4 ppm Se in their drinking water. Compared to the concentrations of intermediates in the livers and kidneys from a control group of rats yoke-fed to the selenium rats, no metabolic changes were observed. It was concluded that growth depression and changes in eating and drinking behavior caused by selenium were not due to enzyme inhibition within glycolysis or the citric acid cycle. The author wishes to thank Mrs. Muriel Pallay and Mrs. Nadya Smejtek for technical assistance.

AB - The concentrations of glycolytic and citric acid cycle intermediates were measured in the livers and kidneys from a selenium group of rats receiving 4 ppm Se in their drinking water. Compared to the concentrations of intermediates in the livers and kidneys from a control group of rats yoke-fed to the selenium rats, no metabolic changes were observed. It was concluded that growth depression and changes in eating and drinking behavior caused by selenium were not due to enzyme inhibition within glycolysis or the citric acid cycle. The author wishes to thank Mrs. Muriel Pallay and Mrs. Nadya Smejtek for technical assistance.

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