Lack of Effect of Selenium on Glycolytic and Citric Acid Cycle Intermediates in Rat Kidney and Liver

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Abstract

The concentrations of glycolytic and citric acid cycle intermediates were measured in the livers and kidneys from a selenium group of rats receiving 4 ppm Se in their drinking water. Compared to the concentrations of intermediates in the livers and kidneys from a control group of rats yoke-fed to the selenium rats, no metabolic changes were observed. It was concluded that growth depression and changes in eating and drinking behavior caused by selenium were not due to enzyme inhibition within glycolysis or the citric acid cycle. The author wishes to thank Mrs. Muriel Pallay and Mrs. Nadya Smejtek for technical assistance.

Original languageEnglish (US)
Pages (from-to)688-691
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume144
Issue number2
DOIs
StatePublished - Nov 1973

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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