Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis

Jeffrey J. Falco, Andrew J. Thomas, Xuan Quin, Shaelene Ashby, Jess C. Mace, Adam S. Deconde, Timothy Smith, Jeremiah A. Alt

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Facial pain is a cardinal symptom of chronic rhinosinusitis (CRS) with significant impacts on patient treatment selection, quality of life, and outcomes. The association between facial pain and CRS disease severity has not been systematically evaluated with validated, facial pain-specific questionnaires. Our objective was to measure pain location, severity, and interference in patients with CRS, and correlate these to the location and severity of radiographic evidence of disease. Methods: Patients with CRS were enrolled into a prospective, cross-sectional study. Patients completed the Brief Pain Inventory Short Form, which is a validated and widely used tool that measures pain location, severity, and interference with daily activities of living. The Lund-Mackay (L-M) computed tomography (CT) scoring system was used to operationalize the radiographic location and severity of inflammation. Facial pain location, severity, and interference scores were correlated to paranasal sinus opacification scores. Results: Consecutive patients with CRS with nasal polyps (CRSwNP; n = 37) and CRS without nasal polyps (CRSsNP; n = 46) were enrolled. No significant relationship was found between the location and severity of reported facial pain and radiographic findings of disease for patients with either CRSwNP or CRSsNP. There was no difference in pain location between patients with and without radiographic disease in a given sinus. Conclusion: Facial pain in CRS is not predicted by the radiographic extent of disease. The location and severity of facial pain reported by the patient is not a reliable marker of the anatomic location and severity of sinonasal inflammation. Pain location should not necessarily be relied upon for guiding targeted therapy.

Original languageEnglish (US)
JournalInternational Forum of Allergy and Rhinology
DOIs
StateAccepted/In press - 2016

Fingerprint

Facial Pain
Chronic Disease
Pain
Nasal Polyps
Inflammation
Paranasal Sinuses
Activities of Daily Living
Patient Selection
Cross-Sectional Studies
Tomography
Quality of Life
Equipment and Supplies
Therapeutics

Keywords

  • Chronic disease
  • Facial pain
  • Facial pressure
  • Quality of life
  • Sinusitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Otorhinolaryngology

Cite this

Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis. / Falco, Jeffrey J.; Thomas, Andrew J.; Quin, Xuan; Ashby, Shaelene; Mace, Jess C.; Deconde, Adam S.; Smith, Timothy; Alt, Jeremiah A.

In: International Forum of Allergy and Rhinology, 2016.

Research output: Contribution to journalArticle

Falco, Jeffrey J. ; Thomas, Andrew J. ; Quin, Xuan ; Ashby, Shaelene ; Mace, Jess C. ; Deconde, Adam S. ; Smith, Timothy ; Alt, Jeremiah A. / Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis. In: International Forum of Allergy and Rhinology. 2016.
@article{d372e994834b4c618b6cb1b8daf3be42,
title = "Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis",
abstract = "Background: Facial pain is a cardinal symptom of chronic rhinosinusitis (CRS) with significant impacts on patient treatment selection, quality of life, and outcomes. The association between facial pain and CRS disease severity has not been systematically evaluated with validated, facial pain-specific questionnaires. Our objective was to measure pain location, severity, and interference in patients with CRS, and correlate these to the location and severity of radiographic evidence of disease. Methods: Patients with CRS were enrolled into a prospective, cross-sectional study. Patients completed the Brief Pain Inventory Short Form, which is a validated and widely used tool that measures pain location, severity, and interference with daily activities of living. The Lund-Mackay (L-M) computed tomography (CT) scoring system was used to operationalize the radiographic location and severity of inflammation. Facial pain location, severity, and interference scores were correlated to paranasal sinus opacification scores. Results: Consecutive patients with CRS with nasal polyps (CRSwNP; n = 37) and CRS without nasal polyps (CRSsNP; n = 46) were enrolled. No significant relationship was found between the location and severity of reported facial pain and radiographic findings of disease for patients with either CRSwNP or CRSsNP. There was no difference in pain location between patients with and without radiographic disease in a given sinus. Conclusion: Facial pain in CRS is not predicted by the radiographic extent of disease. The location and severity of facial pain reported by the patient is not a reliable marker of the anatomic location and severity of sinonasal inflammation. Pain location should not necessarily be relied upon for guiding targeted therapy.",
keywords = "Chronic disease, Facial pain, Facial pressure, Quality of life, Sinusitis",
author = "Falco, {Jeffrey J.} and Thomas, {Andrew J.} and Xuan Quin and Shaelene Ashby and Mace, {Jess C.} and Deconde, {Adam S.} and Timothy Smith and Alt, {Jeremiah A.}",
year = "2016",
doi = "10.1002/alr.21797",
language = "English (US)",
journal = "International Forum of Allergy and Rhinology",
issn = "2042-6976",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis

AU - Falco, Jeffrey J.

AU - Thomas, Andrew J.

AU - Quin, Xuan

AU - Ashby, Shaelene

AU - Mace, Jess C.

AU - Deconde, Adam S.

AU - Smith, Timothy

AU - Alt, Jeremiah A.

PY - 2016

Y1 - 2016

N2 - Background: Facial pain is a cardinal symptom of chronic rhinosinusitis (CRS) with significant impacts on patient treatment selection, quality of life, and outcomes. The association between facial pain and CRS disease severity has not been systematically evaluated with validated, facial pain-specific questionnaires. Our objective was to measure pain location, severity, and interference in patients with CRS, and correlate these to the location and severity of radiographic evidence of disease. Methods: Patients with CRS were enrolled into a prospective, cross-sectional study. Patients completed the Brief Pain Inventory Short Form, which is a validated and widely used tool that measures pain location, severity, and interference with daily activities of living. The Lund-Mackay (L-M) computed tomography (CT) scoring system was used to operationalize the radiographic location and severity of inflammation. Facial pain location, severity, and interference scores were correlated to paranasal sinus opacification scores. Results: Consecutive patients with CRS with nasal polyps (CRSwNP; n = 37) and CRS without nasal polyps (CRSsNP; n = 46) were enrolled. No significant relationship was found between the location and severity of reported facial pain and radiographic findings of disease for patients with either CRSwNP or CRSsNP. There was no difference in pain location between patients with and without radiographic disease in a given sinus. Conclusion: Facial pain in CRS is not predicted by the radiographic extent of disease. The location and severity of facial pain reported by the patient is not a reliable marker of the anatomic location and severity of sinonasal inflammation. Pain location should not necessarily be relied upon for guiding targeted therapy.

AB - Background: Facial pain is a cardinal symptom of chronic rhinosinusitis (CRS) with significant impacts on patient treatment selection, quality of life, and outcomes. The association between facial pain and CRS disease severity has not been systematically evaluated with validated, facial pain-specific questionnaires. Our objective was to measure pain location, severity, and interference in patients with CRS, and correlate these to the location and severity of radiographic evidence of disease. Methods: Patients with CRS were enrolled into a prospective, cross-sectional study. Patients completed the Brief Pain Inventory Short Form, which is a validated and widely used tool that measures pain location, severity, and interference with daily activities of living. The Lund-Mackay (L-M) computed tomography (CT) scoring system was used to operationalize the radiographic location and severity of inflammation. Facial pain location, severity, and interference scores were correlated to paranasal sinus opacification scores. Results: Consecutive patients with CRS with nasal polyps (CRSwNP; n = 37) and CRS without nasal polyps (CRSsNP; n = 46) were enrolled. No significant relationship was found between the location and severity of reported facial pain and radiographic findings of disease for patients with either CRSwNP or CRSsNP. There was no difference in pain location between patients with and without radiographic disease in a given sinus. Conclusion: Facial pain in CRS is not predicted by the radiographic extent of disease. The location and severity of facial pain reported by the patient is not a reliable marker of the anatomic location and severity of sinonasal inflammation. Pain location should not necessarily be relied upon for guiding targeted therapy.

KW - Chronic disease

KW - Facial pain

KW - Facial pressure

KW - Quality of life

KW - Sinusitis

UR - http://www.scopus.com/inward/record.url?scp=84978647646&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978647646&partnerID=8YFLogxK

U2 - 10.1002/alr.21797

DO - 10.1002/alr.21797

M3 - Article

C2 - 27438938

AN - SCOPUS:84978647646

JO - International Forum of Allergy and Rhinology

JF - International Forum of Allergy and Rhinology

SN - 2042-6976

ER -