Lack of correlation between coronary artery calcium and myocardial perfusion imaging

Jonathan Rosman; Michael Shapiro; Anuragini Pandey; Andrew VanTosh; Steven R. Bergmann

doi:10.1016/j.nuclcard.2006.01.023

Lack of correlation between coronary artery calcium and myocardial perfusion imaging

Jonathan Rosman, Michael Shapiro, Anuragini Pandey, Andrew VanTosh, Steven R. Bergmann

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Background: Coronary artery calcium (CAC) provides evidence of coronary atherosclerosis and has significant prognostic power. Although prior studies have documented a relationship between CAC and hemodynamically significant coronary artery stenosis, the results have not been conclusive. Methods and Results: We evaluated 126 consecutive patients who underwent electron beam computed tomography CAC scoring by use of the Agatston method and stress myocardial perfusion imaging (MPI) within 3 months of each other. The analysis revealed no correlation between absolute CAC score and age- and gender-adjusted CAC scores with MPI. Overall, 18% of patients had abnormal MPI results irrespective of their CAC. Conclusion: CAC scoring and stress MPI should be thus considered complementary approaches rather than exclusionary in the evaluation of the patient at risk for coronary artery disease.

Original language	English (US)
Pages (from-to)	333-337
Number of pages	5
Journal	Journal of Nuclear Cardiology
Volume	13
Issue number	3
DOIs	https://doi.org/10.1016/j.nuclcard.2006.01.023
State	Published - Jun 1 2006

Keywords

Myocardial perfusion imaging
atherosclerosis
coronary artery disease
single photon emission computed tomography

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1016/j.nuclcard.2006.01.023

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title = "Lack of correlation between coronary artery calcium and myocardial perfusion imaging",

abstract = "Background: Coronary artery calcium (CAC) provides evidence of coronary atherosclerosis and has significant prognostic power. Although prior studies have documented a relationship between CAC and hemodynamically significant coronary artery stenosis, the results have not been conclusive. Methods and Results: We evaluated 126 consecutive patients who underwent electron beam computed tomography CAC scoring by use of the Agatston method and stress myocardial perfusion imaging (MPI) within 3 months of each other. The analysis revealed no correlation between absolute CAC score and age- and gender-adjusted CAC scores with MPI. Overall, 18% of patients had abnormal MPI results irrespective of their CAC. Conclusion: CAC scoring and stress MPI should be thus considered complementary approaches rather than exclusionary in the evaluation of the patient at risk for coronary artery disease.",

keywords = "Myocardial perfusion imaging, atherosclerosis, coronary artery disease, single photon emission computed tomography",

author = "Jonathan Rosman and Michael Shapiro and Anuragini Pandey and Andrew VanTosh and Bergmann, {Steven R.}",

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doi = "10.1016/j.nuclcard.2006.01.023",

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T1 - Lack of correlation between coronary artery calcium and myocardial perfusion imaging

AU - Rosman, Jonathan

AU - Shapiro, Michael

AU - Pandey, Anuragini

AU - VanTosh, Andrew

AU - Bergmann, Steven R.

PY - 2006/6/1

Y1 - 2006/6/1

N2 - Background: Coronary artery calcium (CAC) provides evidence of coronary atherosclerosis and has significant prognostic power. Although prior studies have documented a relationship between CAC and hemodynamically significant coronary artery stenosis, the results have not been conclusive. Methods and Results: We evaluated 126 consecutive patients who underwent electron beam computed tomography CAC scoring by use of the Agatston method and stress myocardial perfusion imaging (MPI) within 3 months of each other. The analysis revealed no correlation between absolute CAC score and age- and gender-adjusted CAC scores with MPI. Overall, 18% of patients had abnormal MPI results irrespective of their CAC. Conclusion: CAC scoring and stress MPI should be thus considered complementary approaches rather than exclusionary in the evaluation of the patient at risk for coronary artery disease.

AB - Background: Coronary artery calcium (CAC) provides evidence of coronary atherosclerosis and has significant prognostic power. Although prior studies have documented a relationship between CAC and hemodynamically significant coronary artery stenosis, the results have not been conclusive. Methods and Results: We evaluated 126 consecutive patients who underwent electron beam computed tomography CAC scoring by use of the Agatston method and stress myocardial perfusion imaging (MPI) within 3 months of each other. The analysis revealed no correlation between absolute CAC score and age- and gender-adjusted CAC scores with MPI. Overall, 18% of patients had abnormal MPI results irrespective of their CAC. Conclusion: CAC scoring and stress MPI should be thus considered complementary approaches rather than exclusionary in the evaluation of the patient at risk for coronary artery disease.

KW - Myocardial perfusion imaging

KW - atherosclerosis

KW - coronary artery disease

KW - single photon emission computed tomography

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Lack of correlation between coronary artery calcium and myocardial perfusion imaging

Abstract

Keywords

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