Kainic acid induces mitoses in mature retinal neurones in rats

Simmons Lessell, Joseph L. Craft, Daniel M. Albert

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Injection of kainic acid into the vitreous of rats causes mitoses to develop in the inner nuclear layer of the retina. The mitoses appear to be in amacrine cells. Sustained depolarization, which has been shown to be mitogenic for spinal cord neurones cultured in vitro, is presumably the mitogenic stimulus in retinal neurones exposed to kainic acid.

Original languageEnglish (US)
Pages (from-to)731-738
Number of pages8
JournalExperimental Eye Research
Volume30
Issue number6
DOIs
StatePublished - Jun 1980

Keywords

  • amacrine cells
  • electron microscopy
  • kainic acid
  • mitoses
  • retina

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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