Kainic acid induces mitoses in mature retinal neurones in rats

Simmons Lessell, Joseph L. Craft, Daniel Albert

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Injection of kainic acid into the vitreous of rats causes mitoses to develop in the inner nuclear layer of the retina. The mitoses appear to be in amacrine cells. Sustained depolarization, which has been shown to be mitogenic for spinal cord neurones cultured in vitro, is presumably the mitogenic stimulus in retinal neurones exposed to kainic acid.

Original languageEnglish (US)
Pages (from-to)731-738
Number of pages8
JournalExperimental Eye Research
Volume30
Issue number6
DOIs
StatePublished - Jan 1 1980
Externally publishedYes

Fingerprint

Retinal Neurons
Kainic Acid
Mitosis
Amacrine Cells
Retina
Spinal Cord
Neurons
Injections
In Vitro Techniques

Keywords

  • amacrine cells
  • electron microscopy
  • kainic acid
  • mitoses
  • retina

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Kainic acid induces mitoses in mature retinal neurones in rats. / Lessell, Simmons; Craft, Joseph L.; Albert, Daniel.

In: Experimental Eye Research, Vol. 30, No. 6, 01.01.1980, p. 731-738.

Research output: Contribution to journalArticle

Lessell, Simmons ; Craft, Joseph L. ; Albert, Daniel. / Kainic acid induces mitoses in mature retinal neurones in rats. In: Experimental Eye Research. 1980 ; Vol. 30, No. 6. pp. 731-738.
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