Juvenile Chronic Granulocytic Leukemia

Emphasis on Cutaneous Manifestations and Underlying Neurofibromatosis

Jane A. Mays, Robert C. Neerhout, Grover C. Bagby, Robert D. Koler

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Five patients with juvenile chronic granulocytic leukemia are described. Two patients had multiple cafe-au-lait spots compatible with von Recklinghausen’s neurofibromatosis, and three had cutaneous xanthomata. Recurrent cutaneous leukemic infiltrates were noted in two patients. The clinical course of all five patients was characterized by recurrent respiratory symptoms and pulmonary infiltrates that responded to antileukemic therapy in three. Chemotherapy controlled the symptoms but did not influence the eventually fatal outcome.

Original languageEnglish (US)
Pages (from-to)654-658
Number of pages5
JournalAmerican Journal of Diseases of Children
Volume134
Issue number7
DOIs
StatePublished - 1980
Externally publishedYes

Fingerprint

Skin Manifestations
Neurofibromatoses
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Xanthomatosis
Skin
Fatal Outcome
Drug Therapy
Lung

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Juvenile Chronic Granulocytic Leukemia : Emphasis on Cutaneous Manifestations and Underlying Neurofibromatosis. / Mays, Jane A.; Neerhout, Robert C.; Bagby, Grover C.; Koler, Robert D.

In: American Journal of Diseases of Children, Vol. 134, No. 7, 1980, p. 654-658.

Research output: Contribution to journalArticle

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