Juvenile Chronic Granulocytic Leukemia: Emphasis on Cutaneous Manifestations and Underlying Neurofibromatosis

Jane A. Mays; Robert C. Neerhout; Grover C. Bagby; Robert D. Koler

doi:10.1001/archpedi.1980.02130190022006

Juvenile Chronic Granulocytic Leukemia: Emphasis on Cutaneous Manifestations and Underlying Neurofibromatosis

Jane A. Mays, Robert C. Neerhout, Grover C. Bagby, Robert D. Koler

Hematology & Medical Oncology

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Five patients with juvenile chronic granulocytic leukemia are described. Two patients had multiple cafe-au-lait spots compatible with von Recklinghausen’s neurofibromatosis, and three had cutaneous xanthomata. Recurrent cutaneous leukemic infiltrates were noted in two patients. The clinical course of all five patients was characterized by recurrent respiratory symptoms and pulmonary infiltrates that responded to antileukemic therapy in three. Chemotherapy controlled the symptoms but did not influence the eventually fatal outcome.

Original language	English (US)
Pages (from-to)	654-658
Number of pages	5
Journal	American Journal of Diseases of Children
Volume	134
Issue number	7
DOIs	https://doi.org/10.1001/archpedi.1980.02130190022006
State	Published - Jul 1980

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1001/archpedi.1980.02130190022006

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abstract = "Five patients with juvenile chronic granulocytic leukemia are described. Two patients had multiple cafe-au-lait spots compatible with von Recklinghausen{\textquoteright}s neurofibromatosis, and three had cutaneous xanthomata. Recurrent cutaneous leukemic infiltrates were noted in two patients. The clinical course of all five patients was characterized by recurrent respiratory symptoms and pulmonary infiltrates that responded to antileukemic therapy in three. Chemotherapy controlled the symptoms but did not influence the eventually fatal outcome.",

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Juvenile Chronic Granulocytic Leukemia: Emphasis on Cutaneous Manifestations and Underlying Neurofibromatosis

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ASJC Scopus subject areas

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