Jejunal Infection With Campylobacter

Thomas Ward, Kenneth Klein, Bruce K. Borthistle

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A patient had common variable immunodeficiency, chronic malabsorption, and Campylobacter jejuni infection. Infection was diagnosed by jejunal aspiration. A follow-up jejunal aspirate was culture positive at the same time that a stool culture was negative. Infection resulted in worsening of chronic diarrhea, but it was not associated with clinical features of colitis or proctitis. The duration of infection was prolonged and initial antimicrobial therapy was ineffective. Single drug therapy with erythromycin ethylsuccinate and then chloramphenicol led to the emergence of resistant organisms. After five months of bacterial excretion, combination therapy with metronidazole and neomycin sulfate eliminated the organism. This case emphasizes that the clinical manifestations and response to therapy of C jejuni infection can be altered in immunodeficient patients.

Original languageEnglish (US)
Pages (from-to)1072-1074
Number of pages3
JournalArchives of Internal Medicine
Volume144
Issue number5
DOIs
StatePublished - 1984

Fingerprint

Campylobacter Infections
Infection
Erythromycin Ethylsuccinate
Proctitis
Common Variable Immunodeficiency
Campylobacter jejuni
Neomycin
Metronidazole
Chloramphenicol
Colitis
Diarrhea
Therapeutics
Drug Therapy

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Jejunal Infection With Campylobacter. / Ward, Thomas; Klein, Kenneth; Borthistle, Bruce K.

In: Archives of Internal Medicine, Vol. 144, No. 5, 1984, p. 1072-1074.

Research output: Contribution to journalArticle

Ward, T, Klein, K & Borthistle, BK 1984, 'Jejunal Infection With Campylobacter', Archives of Internal Medicine, vol. 144, no. 5, pp. 1072-1074. https://doi.org/10.1001/archinte.1984.00350170240038
Ward, Thomas ; Klein, Kenneth ; Borthistle, Bruce K. / Jejunal Infection With Campylobacter. In: Archives of Internal Medicine. 1984 ; Vol. 144, No. 5. pp. 1072-1074.
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