TY - JOUR
T1 - ITUG, a sensitive and reliable measure of mobility
AU - Salarian, Arash
AU - Horak, Fay B.
AU - Zampieri, Cris
AU - Carlson-Kuhta, Patricia
AU - Nutt, John G.
AU - Aminian, Kamiar
N1 - Funding Information:
Manuscript received February 18, 2009; revised December 31, 2009; accepted January 25, 2010. First published April 12, 2010; current version published June 09, 2010. This work was supported by the Kinetics Foundation and the National Institutes of Health under Grant AG006457 and Grant DC04082.
PY - 2010/6
Y1 - 2010/6
N2 - Timed Up and Go (TUG) test is a widely used clinical paradigm to evaluate balance and mobility. Although TUG includes several complex subcomponents, namely: sit-to-stand, gait, 180° turn, and turn-to-sit; the only outcome is the total time to perform the task. We have proposed an instrumented TUG, called iTUG, using portable inertial sensors to improve TUG in several ways: automatic detection and separation of subcomponents, detailed analysis of each one of them and a higher sensitivity than TUG. Twelve subjects in early stages of Parkinson's disease (PD) and 12 age matched control subjects were enrolled. Stopwatch measurements did not show a significant difference between the two groups. The iTUG, however, showed a significant difference in cadence between early PD and control subjects (111.1 ± 6.2 versus 120.4 ± 7.6 step/min, p < 0.006) as well as in angular velocity of arm-swing (123 ± 32.0 versus 174.0 ± 50.4° /s, p < 0.005), turning duration (2.18 ± 0.43 versus 1.79 ± 0.27 s, p < 0.023), and time to perform turn-to-sits (2.96 ± 0.68 versus 2.40 ± 0.33 s, p <0.023). By repeating the tests for a second time, the testretest reliability of iTUG was also evaluated. Among the subcomponents of iTUG, gait, turning, and turn-to-sit were the most reliable and sit-to-stand was the least reliable.
AB - Timed Up and Go (TUG) test is a widely used clinical paradigm to evaluate balance and mobility. Although TUG includes several complex subcomponents, namely: sit-to-stand, gait, 180° turn, and turn-to-sit; the only outcome is the total time to perform the task. We have proposed an instrumented TUG, called iTUG, using portable inertial sensors to improve TUG in several ways: automatic detection and separation of subcomponents, detailed analysis of each one of them and a higher sensitivity than TUG. Twelve subjects in early stages of Parkinson's disease (PD) and 12 age matched control subjects were enrolled. Stopwatch measurements did not show a significant difference between the two groups. The iTUG, however, showed a significant difference in cadence between early PD and control subjects (111.1 ± 6.2 versus 120.4 ± 7.6 step/min, p < 0.006) as well as in angular velocity of arm-swing (123 ± 32.0 versus 174.0 ± 50.4° /s, p < 0.005), turning duration (2.18 ± 0.43 versus 1.79 ± 0.27 s, p < 0.023), and time to perform turn-to-sits (2.96 ± 0.68 versus 2.40 ± 0.33 s, p <0.023). By repeating the tests for a second time, the testretest reliability of iTUG was also evaluated. Among the subcomponents of iTUG, gait, turning, and turn-to-sit were the most reliable and sit-to-stand was the least reliable.
KW - Balance
KW - Gait
KW - Mobility
KW - Objective assessment
KW - Wearable sensors
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U2 - 10.1109/TNSRE.2010.2047606
DO - 10.1109/TNSRE.2010.2047606
M3 - Article
C2 - 20388604
AN - SCOPUS:77953252776
SN - 1534-4320
VL - 18
SP - 303
EP - 310
JO - IEEE Transactions on Neural Systems and Rehabilitation Engineering
JF - IEEE Transactions on Neural Systems and Rehabilitation Engineering
IS - 3
M1 - 5446357
ER -