It's not just a phase: Crystallization and x-ray structure determination of bacteriorhodopsin in lipidic cubic phases

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Abstract

Utilization of lipidic cubic phases in the crystallization of bacteriorhodopsin (bR) has yielded long sought after crystals that diffract X-rays to 2 Å resolution. The resulting structure provides new information on the protein conformation and the mechanism of proton translocation. Crystallization of bR via lipidic cubic phases may be a harbinger of new membrane protein crystallization strategies.

Original languageEnglish (US)
Pages (from-to)5-10
Number of pages6
JournalStructure
Volume6
Issue number1
DOIs
StatePublished - Jan 15 1998

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ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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