ITF expression in mouse brain during acquisition of alcohol self-administration

Andrey E. Ryabinin; Ryan K. Bachtell; Pierre Freeman; Fred O. Risinger

doi:10.1016/S0006-8993(00)03251-0

ITF expression in mouse brain during acquisition of alcohol self-administration

Andrey E. Ryabinin, Ryan K. Bachtell, Pierre Freeman, Fred O. Risinger

Behavioral Neuroscience

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Expression of inducible transcription factors (ITFs) c-Fos and FosB was investigated during acquisition of alcohol drinking in C57BL/6J mice. A slight but statistically significant increase in c-Fos expression was found in the Edinger-Westphal nucleus (EW) of animals consuming 2% ethanol/10% sucrose for the first time. Stronger expression of c-Fos in EW was found in animals repeatedly consuming ethanol-containing solutions. These findings underscore the potential importance of EW in alcohol-related behaviors.

Original language	English (US)
Pages (from-to)	192-195
Number of pages	4
Journal	Brain research
Volume	890
Issue number	1
DOIs	https://doi.org/10.1016/S0006-8993(00)03251-0
State	Published - Jan 26 2001

Keywords

Alcoholism
Edinger-Westphal
Immediate early gene

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(00)03251-0

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title = "ITF expression in mouse brain during acquisition of alcohol self-administration",

abstract = "Expression of inducible transcription factors (ITFs) c-Fos and FosB was investigated during acquisition of alcohol drinking in C57BL/6J mice. A slight but statistically significant increase in c-Fos expression was found in the Edinger-Westphal nucleus (EW) of animals consuming 2% ethanol/10% sucrose for the first time. Stronger expression of c-Fos in EW was found in animals repeatedly consuming ethanol-containing solutions. These findings underscore the potential importance of EW in alcohol-related behaviors.",

keywords = "Alcoholism, Edinger-Westphal, Immediate early gene",

author = "Ryabinin, {Andrey E.} and Bachtell, {Ryan K.} and Pierre Freeman and Risinger, {Fred O.}",

note = "Funding Information: This work was supported by NIH grants AA10810, AA10520 and AA10760.",

year = "2001",

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doi = "10.1016/S0006-8993(00)03251-0",

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T1 - ITF expression in mouse brain during acquisition of alcohol self-administration

AU - Ryabinin, Andrey E.

AU - Bachtell, Ryan K.

AU - Freeman, Pierre

AU - Risinger, Fred O.

N1 - Funding Information: This work was supported by NIH grants AA10810, AA10520 and AA10760.

PY - 2001/1/26

Y1 - 2001/1/26

N2 - Expression of inducible transcription factors (ITFs) c-Fos and FosB was investigated during acquisition of alcohol drinking in C57BL/6J mice. A slight but statistically significant increase in c-Fos expression was found in the Edinger-Westphal nucleus (EW) of animals consuming 2% ethanol/10% sucrose for the first time. Stronger expression of c-Fos in EW was found in animals repeatedly consuming ethanol-containing solutions. These findings underscore the potential importance of EW in alcohol-related behaviors.

AB - Expression of inducible transcription factors (ITFs) c-Fos and FosB was investigated during acquisition of alcohol drinking in C57BL/6J mice. A slight but statistically significant increase in c-Fos expression was found in the Edinger-Westphal nucleus (EW) of animals consuming 2% ethanol/10% sucrose for the first time. Stronger expression of c-Fos in EW was found in animals repeatedly consuming ethanol-containing solutions. These findings underscore the potential importance of EW in alcohol-related behaviors.

KW - Alcoholism

KW - Edinger-Westphal

KW - Immediate early gene

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ITF expression in mouse brain during acquisition of alcohol self-administration

Abstract

Keywords

ASJC Scopus subject areas

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