Is there a treatment necessity for lipid disorders of uremic patients?

Bernard Lacour, Jean-Baptiste Roullet, Pascale Beyne, Tilman Drüeke

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In the present review, the role of lipid disturbances is evaluated as a risk factor in the pathogenesis and the potential acceleration of atherosclerosis in uremic patients undergoing long-term hemodialysis. The alteration in high density lipoprotein composition with a decrease in high density lipoprotein cholesterol but a normal apoprotein AI content may have relevance to the atherogenetic process. Moreover, the accumulation of cholesterol-rich, very low density lipoproteins and intermediate density lipoproteins may play a major role in atherosclerosis since these degradation products of triglyceride-rich particles are considered as atherogenic. The hypothesis should be tested whether a correction of the abnormal catabolism of triglyceride-rich lipoproteins in uremic patients leads to a decrease in ischemic vascular events.

Original languageEnglish (US)
Pages (from-to)42-51
Number of pages10
JournalBlood Purification
Volume3
Issue number1-3
DOIs
StatePublished - 1985
Externally publishedYes

Fingerprint

Atherosclerosis
Triglycerides
IDL Lipoproteins
Lipids
VLDL Cholesterol
Apoproteins
HDL Lipoproteins
HDL Cholesterol
Lipoproteins
Blood Vessels
Renal Dialysis
Therapeutics

Keywords

  • Atherosclerosis
  • Hemodialysis patients
  • Lipids
  • Lipoprotein anomalies
  • Uremia

ASJC Scopus subject areas

  • Hematology
  • Nephrology

Cite this

Is there a treatment necessity for lipid disorders of uremic patients? / Lacour, Bernard; Roullet, Jean-Baptiste; Beyne, Pascale; Drüeke, Tilman.

In: Blood Purification, Vol. 3, No. 1-3, 1985, p. 42-51.

Research output: Contribution to journalArticle

Lacour, B, Roullet, J-B, Beyne, P & Drüeke, T 1985, 'Is there a treatment necessity for lipid disorders of uremic patients?', Blood Purification, vol. 3, no. 1-3, pp. 42-51. https://doi.org/10.1159/000169397
Lacour, Bernard ; Roullet, Jean-Baptiste ; Beyne, Pascale ; Drüeke, Tilman. / Is there a treatment necessity for lipid disorders of uremic patients?. In: Blood Purification. 1985 ; Vol. 3, No. 1-3. pp. 42-51.
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