Is there a therapeutic role for blood brain barrier disruption?

E. A. Neuwelt, P. Frenkel

Research output: Contribution to journalEditorial

22 Scopus citations

Abstract

Reversible transient blood-brain barrier disruption appears to be reasonably simple to achieve and fairly safe. One can project exploitation of such a delivery technique not only to the use of cytoreductive drugs for neoplasms in the brain but also for enhanced delivery of antibiotics in central nervous system infections or enzymes in circumstances of inborn errors of metabolism.

Original languageEnglish (US)
Pages (from-to)137-139
Number of pages3
JournalAnnals of internal medicine
Volume93
Issue number1 I
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Internal Medicine

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