Is there a therapeutic role for blood brain barrier disruption?

Edward Neuwelt, P. Frenkel

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Reversible transient blood-brain barrier disruption appears to be reasonably simple to achieve and fairly safe. One can project exploitation of such a delivery technique not only to the use of cytoreductive drugs for neoplasms in the brain but also for enhanced delivery of antibiotics in central nervous system infections or enzymes in circumstances of inborn errors of metabolism.

Original languageEnglish (US)
Pages (from-to)137-139
Number of pages3
JournalAnnals of Internal Medicine
Volume93
Issue number1 I
StatePublished - 1980
Externally publishedYes

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Central Nervous System Infections
Inborn Errors Metabolism
Blood-Brain Barrier
Brain Neoplasms
Anti-Bacterial Agents
Enzymes
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Is there a therapeutic role for blood brain barrier disruption? / Neuwelt, Edward; Frenkel, P.

In: Annals of Internal Medicine, Vol. 93, No. 1 I, 1980, p. 137-139.

Research output: Contribution to journalArticle

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