Is reaction time variability in ADHD mainly at low frequencies?

Sarah Karalunas, Cynthia L. Huang-Pollock, Joel Nigg

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background: Intraindividual variability in reaction times (RT variability) has garnered increasing interest as an indicator of cognitive and neurobiological dysfunction in children with attention deficit hyperactivity disorder (ADHD). Recent theory and research has emphasized specific low-frequency patterns of RT variability. However, whether group differences are specific to low frequencies is not well examined. Method: Two studies are presented. The first is a quantitative review of seven previously published studies that have examined patterns of RT variability in ADHD. The second provides new data from a substantially larger sample of children than in prior studies (NControl = 42; NADHD = 123). The children completed a choice RT task as part of a traditional go/stop task. Fast-Fourier transform analyses were applied to assess patterns of variability. Results: Quantitative review of previous studies indicated that children with ADHD demonstrate more low-frequency variability than non-ADHD controls (Hedge's g =.39; 95% CI:.16-.62), but an equivalent excess variability in a faster frequency comparison band (g =.36; 95% CI:.03-.69), with a trivial and nonsignificant difference between ESs in each band. New data replicated results of the quantitative review with nearly identical effects in the low-frequency (g =.39; 95% CI:.05-.75) and faster frequency comparison bands (g =.40; 95% CI:.04-.74) and no evidence of diagnosis × frequency interaction (p =.954). Conclusions: Results suggest that theories of RT variability in ADHD that focus on low-frequency variability will need to be modified to account for the presence of variability at a broader range of frequencies.

Original languageEnglish (US)
Pages (from-to)536-544
Number of pages9
JournalJournal of Child Psychology and Psychiatry and Allied Disciplines
Volume54
Issue number5
DOIs
StatePublished - May 2013

Fingerprint

Attention Deficit Disorder with Hyperactivity
Fourier Analysis
Research

Keywords

  • ADHD
  • default network
  • intraindividual variability
  • reaction time variability

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Medicine(all)

Cite this

Is reaction time variability in ADHD mainly at low frequencies? / Karalunas, Sarah; Huang-Pollock, Cynthia L.; Nigg, Joel.

In: Journal of Child Psychology and Psychiatry and Allied Disciplines, Vol. 54, No. 5, 05.2013, p. 536-544.

Research output: Contribution to journalArticle

@article{f00517511c6d4f87bcbad90960b67718,
title = "Is reaction time variability in ADHD mainly at low frequencies?",
abstract = "Background: Intraindividual variability in reaction times (RT variability) has garnered increasing interest as an indicator of cognitive and neurobiological dysfunction in children with attention deficit hyperactivity disorder (ADHD). Recent theory and research has emphasized specific low-frequency patterns of RT variability. However, whether group differences are specific to low frequencies is not well examined. Method: Two studies are presented. The first is a quantitative review of seven previously published studies that have examined patterns of RT variability in ADHD. The second provides new data from a substantially larger sample of children than in prior studies (NControl = 42; NADHD = 123). The children completed a choice RT task as part of a traditional go/stop task. Fast-Fourier transform analyses were applied to assess patterns of variability. Results: Quantitative review of previous studies indicated that children with ADHD demonstrate more low-frequency variability than non-ADHD controls (Hedge's g =.39; 95{\%} CI:.16-.62), but an equivalent excess variability in a faster frequency comparison band (g =.36; 95{\%} CI:.03-.69), with a trivial and nonsignificant difference between ESs in each band. New data replicated results of the quantitative review with nearly identical effects in the low-frequency (g =.39; 95{\%} CI:.05-.75) and faster frequency comparison bands (g =.40; 95{\%} CI:.04-.74) and no evidence of diagnosis × frequency interaction (p =.954). Conclusions: Results suggest that theories of RT variability in ADHD that focus on low-frequency variability will need to be modified to account for the presence of variability at a broader range of frequencies.",
keywords = "ADHD, default network, intraindividual variability, reaction time variability",
author = "Sarah Karalunas and Huang-Pollock, {Cynthia L.} and Joel Nigg",
year = "2013",
month = "5",
doi = "10.1111/jcpp.12028",
language = "English (US)",
volume = "54",
pages = "536--544",
journal = "Journal of Child Psychology and Psychiatry and Allied Disciplines",
issn = "0021-9630",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Is reaction time variability in ADHD mainly at low frequencies?

AU - Karalunas, Sarah

AU - Huang-Pollock, Cynthia L.

AU - Nigg, Joel

PY - 2013/5

Y1 - 2013/5

N2 - Background: Intraindividual variability in reaction times (RT variability) has garnered increasing interest as an indicator of cognitive and neurobiological dysfunction in children with attention deficit hyperactivity disorder (ADHD). Recent theory and research has emphasized specific low-frequency patterns of RT variability. However, whether group differences are specific to low frequencies is not well examined. Method: Two studies are presented. The first is a quantitative review of seven previously published studies that have examined patterns of RT variability in ADHD. The second provides new data from a substantially larger sample of children than in prior studies (NControl = 42; NADHD = 123). The children completed a choice RT task as part of a traditional go/stop task. Fast-Fourier transform analyses were applied to assess patterns of variability. Results: Quantitative review of previous studies indicated that children with ADHD demonstrate more low-frequency variability than non-ADHD controls (Hedge's g =.39; 95% CI:.16-.62), but an equivalent excess variability in a faster frequency comparison band (g =.36; 95% CI:.03-.69), with a trivial and nonsignificant difference between ESs in each band. New data replicated results of the quantitative review with nearly identical effects in the low-frequency (g =.39; 95% CI:.05-.75) and faster frequency comparison bands (g =.40; 95% CI:.04-.74) and no evidence of diagnosis × frequency interaction (p =.954). Conclusions: Results suggest that theories of RT variability in ADHD that focus on low-frequency variability will need to be modified to account for the presence of variability at a broader range of frequencies.

AB - Background: Intraindividual variability in reaction times (RT variability) has garnered increasing interest as an indicator of cognitive and neurobiological dysfunction in children with attention deficit hyperactivity disorder (ADHD). Recent theory and research has emphasized specific low-frequency patterns of RT variability. However, whether group differences are specific to low frequencies is not well examined. Method: Two studies are presented. The first is a quantitative review of seven previously published studies that have examined patterns of RT variability in ADHD. The second provides new data from a substantially larger sample of children than in prior studies (NControl = 42; NADHD = 123). The children completed a choice RT task as part of a traditional go/stop task. Fast-Fourier transform analyses were applied to assess patterns of variability. Results: Quantitative review of previous studies indicated that children with ADHD demonstrate more low-frequency variability than non-ADHD controls (Hedge's g =.39; 95% CI:.16-.62), but an equivalent excess variability in a faster frequency comparison band (g =.36; 95% CI:.03-.69), with a trivial and nonsignificant difference between ESs in each band. New data replicated results of the quantitative review with nearly identical effects in the low-frequency (g =.39; 95% CI:.05-.75) and faster frequency comparison bands (g =.40; 95% CI:.04-.74) and no evidence of diagnosis × frequency interaction (p =.954). Conclusions: Results suggest that theories of RT variability in ADHD that focus on low-frequency variability will need to be modified to account for the presence of variability at a broader range of frequencies.

KW - ADHD

KW - default network

KW - intraindividual variability

KW - reaction time variability

UR - http://www.scopus.com/inward/record.url?scp=84876296366&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876296366&partnerID=8YFLogxK

U2 - 10.1111/jcpp.12028

DO - 10.1111/jcpp.12028

M3 - Article

VL - 54

SP - 536

EP - 544

JO - Journal of Child Psychology and Psychiatry and Allied Disciplines

JF - Journal of Child Psychology and Psychiatry and Allied Disciplines

SN - 0021-9630

IS - 5

ER -