Is it always unethical to use a placebo in a clinical trial?

Andreas Stang, Hans Werner Hense, Karl Heinz Jöckel, Erick H. Turner, Martin R. Tramèr

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Background to the debate: Placebos are used in trials to conceal whether a treatment is being given or not and hence to control for the psychosomatic effects of offering treatment. Placebo-controlled trials are controversial. Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove the efficacy and safety of many treatments.

Original languageEnglish (US)
Article number3
Pages (from-to)177-180
Number of pages4
JournalPLoS Medicine
Volume2
Issue number3
DOIs
StatePublished - May 18 2005

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Stang, A., Hense, H. W., Jöckel, K. H., Turner, E. H., & Tramèr, M. R. (2005). Is it always unethical to use a placebo in a clinical trial? PLoS Medicine, 2(3), 177-180. [3]. https://doi.org/10.1371/journal.pmed.0020072