Irreversible egfr inhibitor ekb-569 targets low-let γ-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma

Medicine & Life Sciences

• EKB 569 100%
• Squamous Cell Carcinoma 41%
• Cell Death 37%
• Radiation 37%
• Ionizing Radiation 35%
• Apoptosis 6%
• Radiation Exposure 3%
• Immunoblotting 3%
• Transcriptional Activation 3%
• Protein-Tyrosine Kinases 3%
• Signal Transduction 2%
• Radiotherapy 2%
• DNA 2%
• Therapeutics 1%
• Neoplasms 1%

Chemical Compounds

• Ionizing Radiation 59%
• Cell Death 52%
• Pelitinib 37%
• Cell Viability 32%
• Metabolic 26%
• Tyrosine Kinase Inhibitor 22%
• Signal Transduction 17%
• Dose 12%
• Molecule 11%

Agriculture & Biology

• squamous cell carcinoma 68%
• ionizing radiation 57%
• cell death 45%
• apoptosis 15%
• cell viability 10%
• dosage 8%
• radiotherapy 7%
• cells 6%
• transcriptional activation 6%
• in vivo studies 6%
• immunoblotting 5%
• signal transduction 4%
• translation (genetics) 4%
• phosphotransferases (kinases) 4%
• therapeutics 4%
• neoplasms 4%
• DNA 2%