Iron Transport Machinery of Human Cells. Players and Their Interactions

Ningning Zhao, Caroline A. Enns

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Scopus citations

Abstract

Organisms, like cells, maintain tight control of iron. In humans as well as other mammals, control is achieved through the regulation of iron uptake into the body rather than through the excretion of iron. The mechanisms by which humans and mice regulate both iron uptake and the distribution of iron within the body and cells are reviewed. Special emphasis is given to the iron transporters involved in this process.

Original languageEnglish (US)
Title of host publicationCurrent Topics in Membranes
PublisherAcademic Press Inc.
Pages67-93
Number of pages27
DOIs
StatePublished - 2012

Publication series

NameCurrent Topics in Membranes
Volume69
ISSN (Print)1063-5823

Keywords

  • DMT1
  • Ferroportin
  • FLVCR
  • NRAMP1
  • TfR1
  • TfR2
  • Transferrin receptor
  • TRPML1
  • ZIP14

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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  • Cite this

    Zhao, N., & Enns, C. A. (2012). Iron Transport Machinery of Human Cells. Players and Their Interactions. In Current Topics in Membranes (pp. 67-93). (Current Topics in Membranes; Vol. 69). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-394390-3.00003-3