Iron Transport Machinery of Human Cells. Players and Their Interactions

Ningning Zhao, Caroline Enns

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Organisms, like cells, maintain tight control of iron. In humans as well as other mammals, control is achieved through the regulation of iron uptake into the body rather than through the excretion of iron. The mechanisms by which humans and mice regulate both iron uptake and the distribution of iron within the body and cells are reviewed. Special emphasis is given to the iron transporters involved in this process.

Original languageEnglish (US)
Pages (from-to)67-93
Number of pages27
JournalCurrent Topics in Membranes
Volume69
DOIs
StatePublished - 2012

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Iron
Mammals

Keywords

  • DMT1
  • Ferroportin
  • FLVCR
  • NRAMP1
  • TfR1
  • TfR2
  • Transferrin receptor
  • TRPML1
  • ZIP14

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Iron Transport Machinery of Human Cells. Players and Their Interactions. / Zhao, Ningning; Enns, Caroline.

In: Current Topics in Membranes, Vol. 69, 2012, p. 67-93.

Research output: Contribution to journalArticle

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