Involving undergraduates in the annotation and analysis of global gene expression studies: Creation of a maize shoot apical meristem expression database

Brent Buckner, Jon Beck, Kate Browning, Ashleigh Fritz, Lisa Grantham, Eneda Hoxha, Zhian Kamvar, Ashley Lough, Olga Nikolova, Patrick S. Schnable, Michael J. Scanlon, Diane Janick-Buckner

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Through a multi-university and interdisciplinary project we have involved undergraduate biology and computer science research students in the functional annotation of maize genes and the analysis of their microarray expression patterns. We have created a database to house the results of our functional annotation of >4400 genes identified as being differentially regulated in the maize shoot apical meristem (SAM). This database is located at http://sam.truman.edu and is now available for public use. The undergraduate students involved in constructing this unique SAM database received hands-on training in an intellectually challenging environment, which has prepared them for graduate and professional careers in biological sciences. We describe our experiences with this project as a model for effective research-based teaching of undergraduate biology and computer science students, as well as for a rich professional development experience for faculty at predominantly undergraduate institutions.

Original languageEnglish (US)
Pages (from-to)741-747
Number of pages7
JournalGenetics
Volume176
Issue number2
DOIs
StatePublished - Jun 2007
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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