Involvement of phylogenetically conserved acidic amino acid residues in catalysis by an oxidative DNA damage enzyme formamidopyrimidine glycosylase

Medicine & Life Sciences

• Acidic Amino Acids 89%
• Catalysis 71%
• DNA Damage 52%
• 8-hydroxyguanosine 51%
• DNA-(Apurinic or Apyrimidinic Site) Lyase 44%
• 8-hydroxyguanine 43%
• Glutamic Acid 39%
• DNA 33%
• Enzymes 32%
• Aspartic Acid 31%
• Sugars 28%
• sodium borohydride 24%
• Glutamates 23%
• Deoxyribose 23%
• Purines 20%
• Viperidae 20%
• Asparagine 18%
• Sequence Alignment 18%
• Site-Directed Mutagenesis 15%
• Proline 15%
• Amines 15%
• Glutamine 15%
• DNA Repair 13%
• Proteins 5%

Chemical Compounds

• Formamidopyrimidine 100%
• Amino-Acid Residue 53%
• Catalysis 38%
• Aspartic Acid Residue 28%
• Glutamic Acid Residue 27%
• 8-Oxoguanine 15%
• Asparagine 11%
• Glutamine 10%
• Glutamic Acid 10%
• Site-Directed Mutagenesis 10%
• Proline 10%
• Purine 10%
• Secondary Amine 9%
• Amino Groups 8%
• Substitution Reaction 6%
• Protein 4%
• Acid 3%