Investigation of retinal blood flow in glaucoma patients by Doppler Fourier-domain optical coherence tomography

Yimin Wang, Xinbo Zhang, Ou Tan, David Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The measurement of ocular blood flow is important in studying the pathophysiology and treatment of several leading causes of blindness. A pilot study was performed to evaluate the total retinal blood flow in glaucoma patient using Fourier domain optical coherence tomography. For normal people, the measured total retinal flow was between 40.8 and 60.2 μl/minute. We found that eyes with glaucoma had decreased retinal blood flow and average flow veocity, while the venous cross sectional areas were essentially the same as normal. The decrease in blood flow was highly correlated with the severity of visual field loss.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
DOIs
StatePublished - 2011
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV - San Francisco, CA, United States
Duration: Jan 24 2011Jan 26 2011

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7889
ISSN (Print)1605-7422

Other

OtherOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
Country/TerritoryUnited States
CitySan Francisco, CA
Period1/24/111/26/11

Keywords

  • Optical coherence tomography
  • blood flow
  • glaucoma
  • imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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