Investigation of isoprenoid benzoates and naphthoates by reversed-phase liquid chromatography. Isocratic elution characteristics of benzoates and naphthoates of C5C20 terpenoid alcohols

Tsan Hsi Yang, Mark Zabriskie, C. Dale Poulter

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Conditions for derivatization of C5C20 isoprenoid alcohols and the reversedphase liquid chromatographic properties of the corresponding benzoate and naphthoate esters are described. A non-linear response of log k' to changes in the composition of the mobile phase was observed on a RAdial-Pak C18 column. In general, the capacity factors (k') increased with increases in carbon content an degree of saturation inthe hydrocarbon chain, and decreased with increases in branching and Z double bond content. Replacement of a single hydrogen in the methyl group at C-3 of geranyl benzoate with fluorine had little effect on k', while the difluoro- and trifuoromethyl derivatives showed regular increases in k'. The large extinction coefficients of the aromatic ester moieties, especially the 2-naphthoates, provide high sensitivity for UV detection.

Original languageEnglish (US)
Pages (from-to)121-132
Number of pages12
JournalJournal of Chromatography A
Issue numberC
Publication statusPublished - 1984
Externally publishedYes


ASJC Scopus subject areas

  • Analytical Chemistry

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