TY - JOUR
T1 - Investigation of isoprenoid benzoates and naphthoates by reversed-phase liquid chromatography. Isocratic elution characteristics of benzoates and naphthoates of C5C20 terpenoid alcohols
AU - Yang, Tsan Hsi
AU - Zabriskie, T. Mark
AU - Poulter, C. Dale
PY - 1984
Y1 - 1984
N2 - Conditions for derivatization of C5C20 isoprenoid alcohols and the reversedphase liquid chromatographic properties of the corresponding benzoate and naphthoate esters are described. A non-linear response of log k' to changes in the composition of the mobile phase was observed on a RAdial-Pak C18 column. In general, the capacity factors (k') increased with increases in carbon content an degree of saturation inthe hydrocarbon chain, and decreased with increases in branching and Z double bond content. Replacement of a single hydrogen in the methyl group at C-3 of geranyl benzoate with fluorine had little effect on k', while the difluoro- and trifuoromethyl derivatives showed regular increases in k'. The large extinction coefficients of the aromatic ester moieties, especially the 2-naphthoates, provide high sensitivity for UV detection.
AB - Conditions for derivatization of C5C20 isoprenoid alcohols and the reversedphase liquid chromatographic properties of the corresponding benzoate and naphthoate esters are described. A non-linear response of log k' to changes in the composition of the mobile phase was observed on a RAdial-Pak C18 column. In general, the capacity factors (k') increased with increases in carbon content an degree of saturation inthe hydrocarbon chain, and decreased with increases in branching and Z double bond content. Replacement of a single hydrogen in the methyl group at C-3 of geranyl benzoate with fluorine had little effect on k', while the difluoro- and trifuoromethyl derivatives showed regular increases in k'. The large extinction coefficients of the aromatic ester moieties, especially the 2-naphthoates, provide high sensitivity for UV detection.
UR - http://www.scopus.com/inward/record.url?scp=0021765613&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021765613&partnerID=8YFLogxK
U2 - 10.1016/S0021-9673(01)92769-4
DO - 10.1016/S0021-9673(01)92769-4
M3 - Article
C2 - 6526864
AN - SCOPUS:0021765613
SN - 0021-9673
VL - 312
SP - 121
EP - 132
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - C
ER -