Invasive aspergillosis of the airways: Radiographic, CT, and pathologic findings

P. Mark Logan, Steven L. Primack, Roberta R. Miller, Nestor L. Müller

Research output: Contribution to journalArticle

132 Scopus citations

Abstract

PURPOSE: To assess the radiographic, computed tomographic (CT), and pathologic findings in invasive aspergillosis of the airways. MATERIALS AND METHODS: The study included nine consecutive patients (aged 17-65 years [median, 49 years]) with pathologically proved invasive aspergillosis of the airways. All nine underwent chest radiography and seven underwent CT within 3 days of diagnosis. RESULTS: The radiographic findings include normal parenchyma (n = 1), unilateral consolidation (n = 1), bilateral consolidation (n = 5), and ill-defined nodules (n = 2). The main findings at CT included lobar consolidation (n = 1), bilateral predominantly peribronchial consolidation (n = 3), ground-glass attenuation (n = 1), and centrilobular nodules less than 5 mm in diameter (n = 2). At pathologic examination, the peribronchial infiltrates represented bronchopneumonia and the nodules represented Aspergillus bronchiolitis with a variable degree of peribronchiolar organizing pneumonia and hemorrhage. CONCLUSION: Radiographic findings of invasive aspergillosis of the airways consist of consolidation or ill-defined nodules. At CT, the consolidation can be seen to be peribronchial and the nodules centrilobular.

Original languageEnglish (US)
Pages (from-to)383-388
Number of pages6
JournalRADIOLOGY
Volume193
Issue number2
DOIs
StatePublished - Nov 1994

Keywords

  • Aspergillosis
  • Bronchi, infection
  • Lung, infection

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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