Intravenous ferric derisomaltose for the treatment of iron deficiency anemia

Michael Auerbach, David Henry, Thomas G. DeLoughery

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Intravenous (IV) iron is the therapy of choice when oral iron is ineffective or poorly tolerated, yet use has been limited by fears of hypersensitivity reactions (HSRs). Newer formulations that bind iron more tightly and release it more slowly have made the risk of serious or severe HSRs very low. One such formulation, ferric derisomaltose, has been approved in the United States for delivery of 1000 mg iron in a single IV infusion. Ferric derisomaltose rapidly repletes iron parameters with low rates of serious or severe HSRs. Single-infusion iron repletion offers convenience, eliminates adherence concerns, and reduces healthcare resource utilization.

Original languageEnglish (US)
Pages (from-to)727-734
Number of pages8
JournalAmerican Journal of Hematology
Issue number6
StatePublished - Jun 1 2021

ASJC Scopus subject areas

  • Hematology


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