TY - JOUR
T1 - Intravenous agents and intraoperative neuroprotection
T2 - Beyond barbiturates
AU - Cheng, M. A.
AU - Theard, M. A.
AU - Tempelhoff, R.
PY - 1997
Y1 - 1997
N2 - The authors discuss the role of intravenous anesthetic agents in brain protection. The newer intravenous anesthetics, etomidate and propofol, have been proposed as neuroprotective agents. Thiopental remains the drug of choice, however, for use prior to intraoperative ischemic events. The anesthetic ketamine presents surprising similarities to other N-methyl-D- aspartate receptor inhibitors, but remains controversial in its use in neurologically compromised patients.
AB - The authors discuss the role of intravenous anesthetic agents in brain protection. The newer intravenous anesthetics, etomidate and propofol, have been proposed as neuroprotective agents. Thiopental remains the drug of choice, however, for use prior to intraoperative ischemic events. The anesthetic ketamine presents surprising similarities to other N-methyl-D- aspartate receptor inhibitors, but remains controversial in its use in neurologically compromised patients.
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U2 - 10.1016/S0749-0704(05)70301-8
DO - 10.1016/S0749-0704(05)70301-8
M3 - Article
C2 - 9012581
AN - SCOPUS:0031021493
VL - 13
SP - 185
EP - 199
JO - Critical Care Clinics
JF - Critical Care Clinics
SN - 0749-0704
IS - 1
ER -