Intrauterine progestins, progesterone antagonists, and receptor modulators: a review of gynecologic applications

Maria Rodriguez, Meredith Warden, Philip D. Darney

Research output: Contribution to journalArticle

12 Scopus citations


Intrauterine progestins, progesterone receptor modulators, and antagonists have many important current and potential gynecologic applications. This article will describe the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. We will review the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, adenomyosis treatment, uterine fibroids, endometrial hyperplasia, and its concurrent use in women on hormone replacement therapy or tamoxifen.

Original languageEnglish (US)
Pages (from-to)420-428
Number of pages9
JournalAmerican Journal of Obstetrics and Gynecology
Issue number5
Publication statusPublished - May 2010
Externally publishedYes



  • intrauterine progestin
  • leiomyomas
  • levonorgestrel intrauterine device
  • menorrhagia
  • progesterone receptor modulators

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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