Objective: To assess the efficacy of intrauterine insemination (IUI) in a donor insemination program. Design: Prospective randomized clinical trial. Setting: Donor insemination program. Patients, Participants: Women undergoing insemination were randomly assigned to receive either IUI or intracervical insemination for a maximum of six cycles. Interventions: None. Main Outcome Measure(s): Cycle fecundity rates between the two routes were compared. Results: The monthly fecundity rate for intracervical insemination was 5.1% compared with 23% by IUI. By life table analysis, pregnancy rates for IUI were significantly higher than intracervical insemination (P = 0.02). Conclusions: Intrauterine insemination with quarantined donor sperm is superior to intracervical insemination.
- Route of insemination
- intrauterine insemination with frozen donor semen
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology