TY - JOUR
T1 - Intraoperative Neurophysiologic Monitoring for Adult Patients Undergoing Posterior Spinal Fusion
AU - Agarwal, Nitin
AU - Hamilton, D. Kojo
AU - Ozpinar, Alp
AU - Choi, Phillip
AU - Hart, Robert
AU - Yaylali, Ilker
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Background Somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs) are frequently used to monitor neurologic function during spinal deformity surgery. The sensitivity and specificity of intraoperative neurophysiologic monitoring (IONM) in patients undergoing posterior spinal fusion (PSF) is debatable. Methods A retrospective review of all patients undergoing PSF with IONM from October 2008 to December 2012 was performed. Factors including sex, operative time, and spinal levels of posterior fusion were analyzed as risk factors for intraoperative alerts. Results A total of 784 consecutive patients who underwent PSF with IONM without any baseline deficits were analyzed. Patients included 45% men (n = 356) and 55% women (n = 428), with a mean age of 56 years. The mean procedure time was 7 hours. Intraoperative alerts were noted for 3.3% (n = 26) of patients. In this cohort, the average number of levels involved per procedure was approximately 7, ranging from 1 to 16 levels. Of all the spinal levels, the cervicothoracic region had the highest incidence of intraoperative alerts (6 of 97 cervicothoracic cases, P = 0.06). Among these patients, age (P = 0.32), sex (P = 0.66), and procedure time (P = 0.63) were not predictive factors. Four out of 26 (15%) patients had neurologic deficits despite surgeon intervention after neuromonitoring alerts. Conclusions SSEP and MEP changes occurred in 3.3% of patients undergoing PSF, with the highest incidence at the cervicothoracic level. Twenty-three out of 26 patients with intraoperative neuromonitoring changes had improvements in IONM signals after interventions during surgery. Further studies using larger patient numbers may be useful in establishing the utility of neuromonitoring in PSF.
AB - Background Somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs) are frequently used to monitor neurologic function during spinal deformity surgery. The sensitivity and specificity of intraoperative neurophysiologic monitoring (IONM) in patients undergoing posterior spinal fusion (PSF) is debatable. Methods A retrospective review of all patients undergoing PSF with IONM from October 2008 to December 2012 was performed. Factors including sex, operative time, and spinal levels of posterior fusion were analyzed as risk factors for intraoperative alerts. Results A total of 784 consecutive patients who underwent PSF with IONM without any baseline deficits were analyzed. Patients included 45% men (n = 356) and 55% women (n = 428), with a mean age of 56 years. The mean procedure time was 7 hours. Intraoperative alerts were noted for 3.3% (n = 26) of patients. In this cohort, the average number of levels involved per procedure was approximately 7, ranging from 1 to 16 levels. Of all the spinal levels, the cervicothoracic region had the highest incidence of intraoperative alerts (6 of 97 cervicothoracic cases, P = 0.06). Among these patients, age (P = 0.32), sex (P = 0.66), and procedure time (P = 0.63) were not predictive factors. Four out of 26 (15%) patients had neurologic deficits despite surgeon intervention after neuromonitoring alerts. Conclusions SSEP and MEP changes occurred in 3.3% of patients undergoing PSF, with the highest incidence at the cervicothoracic level. Twenty-three out of 26 patients with intraoperative neuromonitoring changes had improvements in IONM signals after interventions during surgery. Further studies using larger patient numbers may be useful in establishing the utility of neuromonitoring in PSF.
KW - Intraoperative neurophysiologic monitoring
KW - Motor evoked potentials
KW - Posterior spinal fusion
KW - Somatosensory evoked potentials
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U2 - 10.1016/j.wneu.2016.11.136
DO - 10.1016/j.wneu.2016.11.136
M3 - Article
C2 - 27923761
AN - SCOPUS:85010223234
SN - 1878-8750
VL - 99
SP - 267
EP - 274
JO - World Neurosurgery
JF - World Neurosurgery
ER -