Intraluminal laser atherectomy with ultrasound and electromagnetic guidance

K. W. Gregory, H. T. Aretz

Research output: Contribution to journalConference articlepeer-review

5 Scopus citations


The Magellan coronary laser atherectomy system is described. It uses high-resolution ultrasound imaging and electromagnetic sensing to provide real-time guidance and control of laser therapy in the coronary arteries. The system consists of a flexible catheter, an electromagnetic navigation antenna, a sensor signal processor and a computer for image processing and display. The small, flexible catheter combines an ultrasound transducer and laser delivery optics, aimed at the artery wall, and an electromagnetic receiving sensor. An extra-corporeal electromagnetic transmit antenna, in combination with catheter sensors, locates the position of the ultrasound and laser beams in the artery. Navigation and ultrasound data are processed electronically to produce real-time, transverse and axial cross-section images of the artery wall at selected locations. By exploiting the ability of ultrasound to image beneath the surface of artery walls, it is possible to identify candidate treatment sites and perform safe radial laser debulking of atherosclerotic plaque with reduced danger of perforation. The utility of the system in plaque identification and ablation is demonstrated with imaging and experimental results.

Original languageEnglish (US)
Pages (from-to)217-225
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jan 1 1991
Externally publishedYes
EventProceedings of Diagnostic and Therapeutic Cardiovascular Interventions - Los Angeles, CA, USA
Duration: Jan 20 1991Jan 22 1991

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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