Intimate combination of low- and high-resolution image data

I. Real- space PET and 1H2O MRI, PETAMRI

Manoj Sammi, Christoph A. Felder, Joanna S. Fowler, Jing Huei Lee, Alejandro V. Levy, Xin Li, Jean Logan, Ildikó Pályka, William Rooney, Nora D. Volkow, Gene Jack Wang, Charles Jr Springer

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial 18FDG PET and 1H2O MR images of the human brain are used as the low- and high-resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low-resolution image type is coded as hue, while that of the high-resolution type is coded as value, a reasonably independent parameter. Furthermore, the high- resolution image must have high contrast and be quantitative in the same sense as the low-resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative 1H2O spin-density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of 18FDG PET images with gray-matter (GM) relaxographic 1H2O images produces visually 'GM-edited' 18SFDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of 1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images.

Original languageEnglish (US)
Pages (from-to)345-360
Number of pages16
JournalMagnetic Resonance in Medicine
Volume42
Issue number2
DOIs
StatePublished - 1999
Externally publishedYes

Fingerprint

Color
Fluorodeoxyglucose F18
Positron-Emission Tomography
Magnetic Resonance Spectroscopy
Brain
Gray Matter

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Intimate combination of low- and high-resolution image data : I. Real- space PET and 1H2O MRI, PETAMRI. / Sammi, Manoj; Felder, Christoph A.; Fowler, Joanna S.; Lee, Jing Huei; Levy, Alejandro V.; Li, Xin; Logan, Jean; Pályka, Ildikó; Rooney, William; Volkow, Nora D.; Wang, Gene Jack; Springer, Charles Jr.

In: Magnetic Resonance in Medicine, Vol. 42, No. 2, 1999, p. 345-360.

Research output: Contribution to journalArticle

Sammi, Manoj ; Felder, Christoph A. ; Fowler, Joanna S. ; Lee, Jing Huei ; Levy, Alejandro V. ; Li, Xin ; Logan, Jean ; Pályka, Ildikó ; Rooney, William ; Volkow, Nora D. ; Wang, Gene Jack ; Springer, Charles Jr. / Intimate combination of low- and high-resolution image data : I. Real- space PET and 1H2O MRI, PETAMRI. In: Magnetic Resonance in Medicine. 1999 ; Vol. 42, No. 2. pp. 345-360.
@article{6e04062a4a104be1a1bd4909d4a051b4,
title = "Intimate combination of low- and high-resolution image data: I. Real- space PET and 1H2O MRI, PETAMRI",
abstract = "Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial 18FDG PET and 1H2O MR images of the human brain are used as the low- and high-resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low-resolution image type is coded as hue, while that of the high-resolution type is coded as value, a reasonably independent parameter. Furthermore, the high- resolution image must have high contrast and be quantitative in the same sense as the low-resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative 1H2O spin-density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of 18FDG PET images with gray-matter (GM) relaxographic 1H2O images produces visually 'GM-edited' 18SFDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of 1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images.",
author = "Manoj Sammi and Felder, {Christoph A.} and Fowler, {Joanna S.} and Lee, {Jing Huei} and Levy, {Alejandro V.} and Xin Li and Jean Logan and Ildik{\'o} P{\'a}lyka and William Rooney and Volkow, {Nora D.} and Wang, {Gene Jack} and Springer, {Charles Jr}",
year = "1999",
doi = "10.1002/(SICI)1522-2594(199908)42:2<345::AID-MRM17>3.0.CO;2-E",
language = "English (US)",
volume = "42",
pages = "345--360",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "John Wiley and Sons Inc.",
number = "2",

}

TY - JOUR

T1 - Intimate combination of low- and high-resolution image data

T2 - I. Real- space PET and 1H2O MRI, PETAMRI

AU - Sammi, Manoj

AU - Felder, Christoph A.

AU - Fowler, Joanna S.

AU - Lee, Jing Huei

AU - Levy, Alejandro V.

AU - Li, Xin

AU - Logan, Jean

AU - Pályka, Ildikó

AU - Rooney, William

AU - Volkow, Nora D.

AU - Wang, Gene Jack

AU - Springer, Charles Jr

PY - 1999

Y1 - 1999

N2 - Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial 18FDG PET and 1H2O MR images of the human brain are used as the low- and high-resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low-resolution image type is coded as hue, while that of the high-resolution type is coded as value, a reasonably independent parameter. Furthermore, the high- resolution image must have high contrast and be quantitative in the same sense as the low-resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative 1H2O spin-density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of 18FDG PET images with gray-matter (GM) relaxographic 1H2O images produces visually 'GM-edited' 18SFDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of 1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images.

AB - Two different types of (co-registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel-by-pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial 18FDG PET and 1H2O MR images of the human brain are used as the low- and high-resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low-resolution image type is coded as hue, while that of the high-resolution type is coded as value, a reasonably independent parameter. Furthermore, the high- resolution image must have high contrast and be quantitative in the same sense as the low-resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative 1H2O spin-density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of 18FDG PET images with gray-matter (GM) relaxographic 1H2O images produces visually 'GM-edited' 18SFDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of 1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images.

UR - http://www.scopus.com/inward/record.url?scp=0032855313&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032855313&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1522-2594(199908)42:2<345::AID-MRM17>3.0.CO;2-E

DO - 10.1002/(SICI)1522-2594(199908)42:2<345::AID-MRM17>3.0.CO;2-E

M3 - Article

VL - 42

SP - 345

EP - 360

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 2

ER -