Intestinal tissue engineering: From regenerative medicine to model systems

Flavio G. Rocha, Edward E. Whang

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Background Tissue engineering is a rapidly emerging field that combines the established disciplines of engineering, biology, and medicine with the goal of fabricating viable tissues and organs. Although initially targeted for applications in regenerative medicine, a novel application of this technology has been to generate experimental model systems for studying biological mechanisms and testing the efficacy of potential therapies. Methods Review and analysis of the literature. Results and conclusion We present the limitations of existing models and provide examples of how tissue engineering has allowed for the generation of new models that may overcome these limitations.

Original languageEnglish (US)
Pages (from-to)320-325
Number of pages6
JournalJournal of Surgical Research
Issue number2
StatePublished - Aug 2004
Externally publishedYes


  • intestinal regeneration
  • model system
  • tissue engineering

ASJC Scopus subject areas

  • Surgery


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