International normalized ratio in anticoagulant therapy: understanding the issues.

A. L. Severson, L. R. Baldwin, T. G. DeLoughery

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Recently, a change in anticoagulation therapy occurred that is still partially ignored by the healthcare community. Understanding the controversy over the use of the internal normalized ratio in monitoring patients receiving warfarin therapy is important for nurses who provide care to these patients. Five questions related to current monitoring of patients treated with anticoagulants are addressed. Nurses must recognize the importance to their practice of changes in laboratory methods and move toward using the most useful measures available to influence patients' outcomes. The international normalized ratio is the most appropriate way to evaluate the effects of warfarin therapy. All healthcare providers should use this ratio as the standard in evaluating the effects of anticoagulation therapy.

Original languageEnglish (US)
Pages (from-to)88-92; quiz 94
JournalAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses
Issue number2
StatePublished - Mar 1997

ASJC Scopus subject areas

  • Critical Care


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